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Found 1,623 clinical trials
C Carmen Farrelly

Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation Compared to Single Device Treatments in Patients With Diabetes Mellitus

Purpose of this study: The purpose of the study is to find out whether using a drug coated balloon in combination with a drug-eluting stent is better than the standard practice of using either device on its own. This study is specifically looking at patients with diabetes who have coronary …

18 years of age All Phase N/A
E Edward Jude, MD

Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)

Diabetes mellitus is a global problem and regular monitoring of blood sugar control is important to reduce the risk of complications secondary to poor sugar control. To assess control a simple blood test is undertaken called the HbA1c. This test gives an assessment of the person's sugar control over the …

18 years of age All Phase N/A
K Kassiy Pierce

Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

Evaluation of Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

45 - 85 years of age All Phase 4
A Adrian Dumitrascu, MD

Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

The purpose of this research is to prove that data generated by your real-time personal continuous glucose monitors CGMs brought in the hospital at the time of hospitalization can be monitored and safely used to guide insulin therapy aiming to improve glycemic control and to diminish the hypoglycemia and hyperglycemia …

18 years of age All Phase N/A
S Shuang Li, Master

Investigation of Pharmacokinetics and Safety of HRS-7535 in Subjects With Hepatic Impairment and Normal Hepatic Function

The study is being conducted to compare the pharmacokinetics and safety of HRS-7535 in subjects with mild to moderate hepatic impairment and normal hepatic function.

18 - 70 years of age All Phase 1
A Alex Abizaid, MD

Feasibility Study to Evaluate an Intravascular Blood Continuous Glucose Sensor

The goal of this early first in man clinical trial is to evaluate the safety of an implantable continuous blood glucose monitoring system in participants with Diabetes Mellitus. Safety will be assessed by looking at the absence of procedure or device related adverse events. Additionally, the surgical procedure and device …

21 - 75 years of age All Phase N/A
Y Yaowen Hu

Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated Patients

Constipation is the most common gastrointestinal manifestation in diabetic patients. Emerging evidence suggests that gut microbiota dysbiosis may contribute to the pathogenesis of diabetes, highlighting the need to investigate its role in diabetic constipation, though current research remains limited. Current management of diabetic constipation primarily relies on bulk-forming and osmotic …

18 - 70 years of age All Phase N/A
L Long Wang, Dr.

Clinical Evaluation of Non-invasive Blood Glucose Meter

This trial is a prospective, multicenter, non-randomized, open-label, self-controlled, paired design clinical study, which will be conducted in 3 research centers, with a total of 210 subjects enrolled, including diabetic patients aged 18 years and above and some healthy subjects. After screening, each eligible subject will have their blood glucose …

18 years of age All Phase N/A
M Mohamed Mahmoud Dogha, Assistant Professor of Urology

Impact of Pilates Exercises on Diabetic Erectile Dysfunction.

Erectile dysfunction (ED) has a prevalence of 52.5% in diabetic male patients, as described in a meta-analysis of 145 studies, including 88,577 men with type 1 and type 2 diabetes. In men, ED can cause sexual dissatisfaction and distress, unsatisfactory relationships, and marital tension

40 - 60 years of age Male Phase N/A
K Kelly J Feuerhak

Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

Researchers are trying to understand why people with indigestion and diabetes mellitus have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small intestine. As part of this investigation, a medication called ondansetron will also be studied to determine its effects …

18 - 75 years of age All Phase 2

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