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Found 1,604 clinical trials
J Julia K Mader, Assoc. Prof.

FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT

This double-blinded proof-of-concept study is proposed to explore the effects of fecal microbiota transfer (FMT) in human subjects. Here we perform FMTs into obese recipients using stool from lean unoperated donors and from previously obese patients after successfull treatment with bariatric Roux-en-Y Gastric Bypass (RYGB) surgery. Obese patients treated with …

18 - 60 years of age All Phase N/A
D Daniel Kim-Shapiro, PhD

Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )

Nitric Oxide (NO) is an important molecule that is produced naturally in the body and that helps maintain healthy blood flow. Low availability of NO contributes to many diseases while administration of NO is therapeutic. In addition to being made naturally in the body, NO can be obtained through the …

18 - 70 years of age All Phase N/A
J Jorge Araujo-Duran, MD

Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes

A pilot study to evaluate and compare glucose metrics using a real-time continuous glucose monitor (FreeStyle Libre 3 sensor) between patients with diabetes and gastroparesis and those with diabetes without gastroparesis.

18 years of age All Phase N/A
N Neera Ahuja, MD

Food Insecurity Reduction & Strategy Team

This study seeks to address the multifaceted challenges posed by food disparities and their negative consequences on health outcomes, via a comprehensive community health intervention program. Study objectives include: To describe the social-demographic and clinical factors associated with food insecurity in the hospitalized diabetic population. To design, implement and evaluate …

18 years of age All Phase N/A
A Adnan Agha

Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue

Obesity and type 2 Diabetes Mellitus prevalence has doubled in the last 30 years and nearly one fifth of UAE population has Type 2 Diabetes while more than quarter has obesity. Non-alcoholic fatty liver disease is present in more than 30% of patients with type 2 diabetes and in > …

18 - 99 years of age All Phase 1/2
K Kelly Birdwell, MD

Empagliflozin Treatment in Kidney Transplant Recipients

Kidney transplantation improves the health and quality of life for those Veterans with end stage kidney disease (ESKD). While early patient and graft survival are excellent, long-term outcomes continue to be challenging. Patient death with existing kidney graft function occurs in about half of all recipients over time. This is …

19 years of age All Phase 4
L Luciana P Pisani, PhD

Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss

This project aims to offer a quantitative and qualitative nutritional approach, along with educational nutritional guidelines for participants with Non-Communicable Chronic Diseases. The main goals are: 1- Regularization of eating habits and windows; 2- Modulation of biochemical, anthropometric, and cardiovascular parameters; 3- Increase in knowledge about healthy eating. In this …

18 - 80 years of age All Phase N/A
W Weisheng Liu, MD

The Effect of Dapagliflozin on the Short-term Prognosis of Patients With Acute Myocardial Infarction

Dapagliflozin is one of the SGLT-2 inhibiters. Recent clinical trials have demonstrated that SGLT-2 inhibitors are effective for treating heart failure. The DAPA-HF clinical trial has demonstrated that the effects of empagliflozin and dapagliflozin improve renal outcomes and reduce all-cause and cardiovascular death in patients with HFrEF[1]. However, its effect …

40 - 80 years of age All Phase 4
R Risa M Wolf, MD

ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2

The purpose of this study is to determine if use of a nonmydriatic fundus camera using autonomous artificial intelligence software at the point of care increases the proportion of underserved youth with diabetes screened for diabetic retinopathy.

8 - 21 years of age All Phase N/A
M Melissa Gilrain

Go Girls! Fitness Support Group Intervention Effectiveness Study

The main purpose of this study is to determine if the Go Girls! program to take place at the Kluge Children's Rehabilitation Center Therapeutic Recreation Gymnasium, intended to introduce girls to a fun, non-threatening environment of exercise with peer support, improves scores on a physical activity enjoyment scale (PACES). Information …

10 - 18 years of age Female Phase N/A

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