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Found 65,199 clinical trials
A Amr Esam Darwish, MD

Early Prediction of Neoadjuvant Chemotherapy Response in Bladder Cancer Using Quantitative Multiparametric MRI

Bladder cancer is a prevalent malignancy globally, with muscle-invasive disease having a five-year survival rate below 50%. Neoadjuvant chemotherapy (NAC) before radical cystectomy has shown efficacy for resectable muscle-invasive bladder cancer (MIBC). However, non-response to NAC can lead to delayed surgery and unnecessary toxicity. Magnetic resonance imaging (MRI), particularly multiparametric …

18 years of age All Phase N/A
G Gaojun Teng, M.D.

Dynamic Prediction Model for Patients with Unresectable Biliary Malignancies Receiving Systemic Chemotherapy Combined with Immunotherapy: a Multicenter, Observational Study

This study focused on the longitudinal tumor burden profile (tumor macro features, histopathological types and imaging features, etc.), liver function, health status, tumor biomarkers, and serological indicators of patients with unresectable biliary malignancies before chemotherapy combined with immunotherapy to build a dynamic prediction model. Based on this model, risk stratification …

18 years of age All Phase N/A
G Gianluca Ianiro, MD

Outcomes of Outpatients in an Gut Microbiota Clinic

The gut microbiota plays a crucial role in human health, influencing metabolism, immunity, and pathogen resistance. Research has linked microbiome dysbiosis to various intestinal and extra-intestinal disorders, prompting interest in therapeutic strategies like fecal microbiota transplantation (FMT), which is now standard for recurrent Clostridioides difficile infection and shows promise for …

18 years of age All Phase N/A
M Marina Idalia Rojo López Barcelona

Patients' Perspectives on Metabolic Dysfunction-associated Steatohepatitis: a Qualitative Study

The aim of this qualitative study is to explore and identify the expectations, perceptions, attitudes, needs, and knowledge related to the management of metabolic dysfunction-associated steatohepatitis (MASH) in patients diagnosed with this condition, before and after their participation in the MASH-Cardiovascular Programme at Hospital de la Santa Creu i Sant …

18 - 75 years of age All Phase N/A

Pulse Wave Velocity and in Subacute Stroke Patients Following Rehabilitation

Currently, the literature regarding the relationship between Pulse Wave Velocity (PWV) and functional recovery, particularly of upper limb function, in patients with subacute stroke is still limited. Therefore, the aim of the study is to evaluate the changes in baPWV after four weeks of intensive rehabilitation therapy, and the correlation …

18 - 80 years of age All Phase N/A
V Valery Likhvantsev, PhD

Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis

Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients. These disorders can affect cognitive functions for years, deteriorating quality of life and increasing hospital stays and medical costs. Diagnosing PND is challenging due to their varied manifestations, such as memory and attention problems, and …

18 years of age All Phase N/A
T Tekin K Ulku, Assoc. Prof.

Gait Assessment Via Telephone Application

The evaluation of human gait is a crucial component of the clinical assessment and decision-making process. The gold standard in gait analysis is computerized gait analysis, which allows for three-dimensional digital data acquisition through computers (3D Computerized Gait Analysis). However, this technology is not readily accessible in routine analyses, as …

18 - 26 years of age All Phase N/A

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study

Evaluation of potential nerve damage after radial CAG/PCI.

18 years of age All Phase N/A
A Augusta Amaeze

Energy Needs and Nutritional Status of Adolescent Girls

The purpose of this study is to investigate the energy needs and nutritional status of adolescent girls in Abia State, Nigeria

10 - 19 years of age Female Phase N/A
M Murat AKIN, ASSISTANT DOCTOR

The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

In the etıology of Idıopathıc Acute Perıpheral Facıal Palsy, known as bell palsy, many causes have been descrıbed, such as specıfıc ımmune, ıchemıc, ınfectıous and heredıal factors. ın our study, we have observed the blood homocysteıne level that causes thrombotıc dısorders ın paralysıs patıents.

18 - 80 years of age All Phase N/A

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