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Found 65,199 clinical trials
C Chiara Giorgini, MD

Usefulness of Post-Operative Radiotherapy in High-grade Cutaneous Squamous Cell Carcinoma: an Observational Study

Post-operative radiotherapy (PORT) is currently considered as the second most important therapy to treat high-grade cutaneous squamous cell carcinoma. Nonetheless, only few studies evaluate its impact on recurrence rate and the major part of those ones do not include a proper control group of patients. Most recent guide lines from …

18 years of age All Phase N/A
S Susana González-Suárez, MD; PhD

Postoperative Memories and Level of Sedation for Tracheal Intubation Using Fiberoptic Bronchoscopy/Videolaryngoscopy

Antecedentes In patients with expected difficult airways undergoing surgery, tracheal intubation must be performed with a fiberoptic bronchoscope or video laryngoscope while keeping the patient awake and under the effects of anesthetic sedation. Objective: To determine and compare the existence of postoperative memories of the patients and the different levels …

18 years of age All Phase N/A
D Department

ChAracterization of Patients and Treatment OUtcomes in Severe Tricuspid Regurgitation

The goal of this observational study is to characterize the population of patients qualified for transcatheter tricuspid valve interventions (TTVI). It is expected to: Describe the profile of patients qualified for TTVI Establish the most common causes for disqualification from TTVI Evaluate the immediate and long-term efficacy of TTVI Evaluate …

18 years of age All Phase N/A
A Anders Kjellin, MD

Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints

The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints. The degradation of extracellular matrix (ECM) proteins in thumb basal joints will be evaluated in association to the metabolic profile of the patient, but we also aim to compare the …

25 years of age All Phase N/A
H Haixia Jiang

Perioperative IL-33 is Associated with the Early Stage of Postoperative Neurocognitive Dysfunction After Major Abdominal Surgery

Perioperative neurocognitive dysfunction(PND) are common complications of major surgery among patients, could be a long-term disease, which sometimes lasts for several years, and it is meaningful to find a biomarker of PND at the early stage.As far as we know, the relationship between IL-33 and PND is not clear yet …

years of age All Phase N/A

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

The purpose of this study is to characterize participants with Crohn's Disease (CD) and Ulcerative Colitis (UC) treated with Guselkumab in a real-world setting, and to assess the clinical effectiveness (how well the treatment works) in the overall population and in different participant subgroups. Furthermore patient-reported outcomes like fatigue, health-related …

18 years of age All Phase N/A
M Min Yan

The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation

Evaluate the influence of perioperative factors on postoperative outcomes in patients undergoing lung transplantation patients. To evaluate the feasibility of using pulmonary ultrasound to identify lung complications such as atelectasis and pulmonary edema after lung transplantation Observe the changes of perioperative inflammation and immune indexes after lung transplantation

18 years of age All Phase N/A
L Laura Biagi, PhD

7T Anatomo-functional Characterization of Structures in the Action Observation Network

The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical connectivity of the nodes of the AON circuit, using an ultra-high field (7T), high spatial resolution Magnetic Resonance Imaging protocol. The main questions …

11 - 40 years of age All Phase N/A

Registry for Stage 2 Type 1 Diabetes

Stage 2 Type 1 Diabates (T1D) is an early stage of T1D characterized by dysglycemia but not yet leading to clinical symptoms. Progression of the disease to Stage 3 (clinical T1D), leads to overt hyperglycemia requiring eventually exogenous insulin. TZIELD® (teplizumab-mzwv) has been approved to delay onset of stage 3 …

years of age All Phase N/A

Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy

Predicting early onset neuropathy in people with type 1 diabetes

18 - 60 years of age All Phase N/A

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