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Found 65,199 clinical trials

Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor

Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor. These gamma-cameras (which obtained the CE-marking in 2016), offer a technological breakthrough by providing an additional information. They allow "to quantify" for the 1st time in clinical routine conditions, the quantity …

18 years of age All Phase N/A

The Lymphocytic Infiltrate of Lung Tumors.

The study is configured as a monocentric observational transversal biological study. The main objective of the study is the reconstruction of the molecular organization of tumors of the thoracic cavity, in particular non-small cell lung cancer (NSCLC). The study involves the collection of clinical data and biological material (blood and …

18 years of age All Phase N/A

Home Reported Outcomes in PNH

The study aims to longitudinally capture the full spectrum of symptoms, treatment utilization, and overall Health-Related Quality of Life (HRQoL) experienced by PNH patients. By primarily utilizing home reported outcomes (HRO) data on symptom burden and treatment usage, supplemented with patient-reported outcome (PRO) measures, the study seeks to establish a …

18 - 99 years of age All Phase N/A
E Engin ihsan Turan

Video-Based Versus Numerical Pain Assessment in Postoperative Patients: A Pilot Study

The goal of this observational pilot study is to evaluate whether video-based visual scenarios representing different levels of pain are preferred over the traditional Numerical Rating Scale (NRS) by postoperative patients. The study also investigates the clarity and interpretability of both methods and examines the level of agreement between the …

18 years of age All Phase N/A
R René K Støvring, md Phd

Cortisol, Hippocampus, and Insula in Anorexia Nervosa.

EXCENTRICC is a platform for scientific collaboration between different disciplines, all working on a common theme: adrenocortical hormones. In this EXCENTRICC sub-study, associations are studied between cortisol levels and depression, anxiety, disease severity and hippocampal and insula volume in the brain in anorexia nervosa.

18 - 50 years of age Female Phase N/A
A Antonio Curcio, Medicine

Impact of Virtual Reality in Cardiac Electrophysiology

Pain during pacemaker or defibrillator implantation can increase patient discomfort, anxiety, and the need for deeper sedation. Using virtual reality (VR) as a non-pharmacological distraction tool may help reduce perceived pain, stabilize vital signs, and improve the overall patient experience. This prospective, single-center study evaluates whether adding VR to standard …

18 years of age All Phase N/A
N Naomi Litichever, PhD

Histiocytosis and Inflammatory Manifestations in Patients with H Syndrome

H syndrome is a rare genetic disorder predisposing to histiocytosis. Our knowledge of the clinical spectrum of these patients is based on case reports and small patient series. Patients with H syndrome have been treated with a range of immunomodulatory and chemotherapeutic agents, with limited success. We aim to comprehensively …

years of age All Phase N/A
K Kenneth Urish, MD

Functional Recovery After Total Knee Arthroplasty

The goal of this observational study is to learn about patients' recoveries after receiving total knee arthroplasty (TKA). The main questions it aims to answer are: Does robotic-assisted TKA have improved perceived recovery when compared to conventional TKA? Does robotic-assisted TKA lead to improved functional recovery when compared to conventional …

40 - 90 years of age All Phase N/A
J Jakob Wollborn, MD, PhD

Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery

Prospective observational study on quality of life with postoperative atrial fibrillation after cardiac surgery using SF-36 and qualitative questions

18 - 100 years of age All Phase N/A
Q Qian Zhang, Phd

Neural Changes in Stroke Patients During Challenging Walking Tasks.

For stroke patients, a challenging, unfamiliar, and more difficult task may increase the likelihood of brain activation to stimulate recovery. Pedal walking and walking with eyes-covered are both difficult and challenging tasks for stroke patients. The investigators intend to study the biomechanics and neural mechanisms of challenging pedal walking and …

18 - 70 years of age All Phase N/A

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