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Found 65,447 clinical trials
E Emily DeBoer, MD

Pulmonary Health in Children With Down Syndrome

The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.

3 - 18 years of age All Phase N/A
S Sandrine JANDET CARRON

Acceptability and Feasibility of Implementing a Coordinated Hospital/Non-hospital Parenting Support and Prevention Program for Families of Infants at High Neurodevelopmental Risk After Neonatal Intensive Care Hospitalization

The PRéPaR project aims to construct, with the help of parents and early care providers, a support program for the families of infants at an increased risk for neurodevelopmental disorders, and to evaluate the acceptability and feasibility of such a program. This program aims to strengthen parenting skills, support infant …

18 years of age All Phase N/A
A Alastair Forbes, MD

Standardising and Simplifying the Global Leadership Initiative on Malnutrition (GLIM) for Its More General Application

This observational study of aims to test whether and how the results of GLIM change when using different approaches and methods to carry out its components.

18 years of age All Phase N/A

Antibiotic-induced Disruption of the Microbiota

The use of antibiotics causes profound changes in the microbiota. However, the magnitude of the effect of intrapartum and early-life antibiotics on the breast milk and the infant oral and intestinal microbiota, and whether effects are only short-term or persist long-term remain uncertain and will be determined in this study.

1 - 2 years of age All Phase N/A

Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia

The purpose of this study is to collect medical informations and samples from refractory and/or relapsed chronic lymphocytic leukemia during or after venetoclax treatment, in order to evaluate the frequency of resistance mechanisms.

18 years of age All Phase N/A
H Hannah Vandegrift

Prospective 4D CTA of BAV Competence

The study involves annual 4D CTA imaging of the bicuspid aortic valve for a period of 5 years. CTA is often standard of care for BAV patients, but patients in this study will receive a higher radiation dose with a 4D imaging protocol. There may also be patients enrolled in …

18 years of age All Phase N/A
A Astrid Pavlovsky

PET Adapted Treatment of Patients With Limited Stage DLBCL and no Risk Factors

Prospective, multicenter, phase IV study, of real-life evidence destined to evaluate the feasibility and efficacy of performing a treatment adapted to PET-CT in patients with stage I and II DLBCL, without poor prognostic factors.

17 years of age All Phase N/A
B Britt Biesinger, MPH

Gut Microbiota in Metabolic Surgery

Metabolic surgery is an emerging option to treat obesity-related metabolic diseases (e.g., type 2 diabetes) and prevent cardiovascular disease (CVD). Metabolic surgery can profoundly alter the gut microbiota; meanwhile, gut microbiota may affect surgical outcomes. Longitudinal studies that examined pre- to post-surgery changes in gut microbiota and its relation to …

21 - 65 years of age All Phase N/A

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

This is a prospective, observational, multi-center and post-authorization safety study that includes patients with a diagnosis of Neovascular Glaucoma. The investigator will have made the decision to use Eylea for treatment. The objective of this study is to assess safety and effectiveness of Eylea using in real clinical practice. Patients …

years of age All Phase N/A
Y Yan Hu, M.D., Ph.D.

The Role of ctDNA Testing Plus AI-based Pathology in Resectable LSCC

The goal of this observational study is to explore whether ctDNA dynamic monitoring plus AI-based pathology can more effectively predict the therapeutic effect of neoadjuvant chemoimmunotherapy for resectable lung squamous cell carcinoma, so as to accurately guide clinical diagnosis and treatment.

18 - 75 years of age All Phase N/A

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