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Found 65,199 clinical trials
N Nicolas GOLSE, phD

Estimation of Steatosis on Liver Transplants by Intraoperative Spectrometry

The goal is to have a small spectrometer (pocket size) , reliable and rapid tool that can be used during liver harvesting, which enables macrosteatosis to be evaluated reproducibly and selectively, at any time. This tool must be minimally invasive, inexpensive and without significantly impacting the general organization of multi-organ …

18 years of age All Phase N/A

Clinical Predictors of Short Term Outcomes of Ablation of Idiopathic Monomorphic PVCs

Clinical predictors of successful Pvcs ablation

years of age All Phase N/A
B Bernhard Krämer, Prof. Dr.

AI Based Real Time Detection of Endometriosis Lesions

Development of AI-based approaches for automated real-time detection of endometriosis lesions using endoscopic image and video material.

18 years of age Female Phase N/A
J Jake Steenblick, DNP

Duloxetine Metabolism and Fibromyalgia

People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. The degree to which duloxetine is helpful for …

18 years of age All Phase N/A
Y Yasmina CHOUIK, MD

Intra-Hepatic Microbiota in Alcoholic Hepatitis

Alcoholic hepatitis (AH) is a serious complication of alcoholic liver disease (ALD). The histological presentation of AH is characterized by neutrophilic lobular inflammation, macrovesicular steatosis, hepatocyte ballooning and necrosis and the presence of Mallory bodies. In cases of severe HA, defined by a modified Maddrey score of 32 or above, …

18 years of age All Phase N/A
D Daphne Koinis-Mitchell, PhD

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy …

7 - 12 years of age All Phase N/A
H Hannah L Lawton, BSc(Hons) MSc

Exploring Eye Vergence Markers ADHD) and ASD

The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks. Eye vergence, a binocular movement crucial for depth perception, has recently been linked to attentional control and neurodevelopmental conditions …

6 years of age All Phase N/A
Y Yong Xie, Dr.

Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics.

Endovascular Thrombectomy has emerged as a pivotal treatment modality for acute ischemic stroke. However, despite successful thrombus removal, a substantial proportion of patients still experience poor outcomes. Selective intra-arterial cooling has shown promise in decelerating stroke progression and providing neuroprotection. This study aims to identify biomarkers associated with the combination …

18 - 80 years of age All Phase N/A

The Relationship Between Trans-diaphragmatic Pressure and Diaphragmatic Contraction

Through this study the investigators aim to clarify the relationship between trans-diaphragmatic pressure and various parameters of the diaphragmatic contraction evaluated by ultrasound. Moreover, a lung ultrasound exam will be performed at the end of spontaneous breathing, resistive breathing and maximal inspiratory pressure maneuver (MIP) in order to assess with …

18 years of age All Phase N/A
D Damien JOLLY

Study of Vitamin B12 Metabolism in Children With Sickle Cell Disease Exposed to MEOPA

Short description of the protocol intended for the lay public. Include a brief statement of the study hypothesis (Limit : 5000 characters) The sickle cells anemia is a monogenic disease linked to the presence of Hemoglobin S due to a mutation in the Hemoglobin Beta chain. The lack of circulating …

2 - 18 years of age All Phase N/A

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