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Found 65,199 clinical trials
L Li Ya Xu, PhD

Observation of Exhaled VOC Biomarkers Characteristics in Admitted Women with Breast Ultrasound BI-RADS 4 Grade

Explore VOCs indicators that can effectively distinguish between benign and malignant breast diseases. The accuracy of VOCs indicators and ultrasound 4a/4b/4c diagnosis will be compared in determining benign and malignant diseases based on pathological gold standards.

18 - 80 years of age Female Phase N/A
L Laura-Ann Bruton

Diabetes in Primary Care - Improving Classification

This study aims to evaluate the clinical utility and acceptability to patients and practitioners of running diabetes classification algorithms on primary care data to help improve diagnosis of diabetes subtypes in adults diagnosed with diabetes under the age of 50. The outputs from this research will help provide initial data …

18 years of age All Phase N/A
L Laura Hamilton

Reversal of Atrial Substrate to Prevent Atrial Fibrillation Cohort Study

Atrial fibrillation (AF) is a major health problem, with a prevalence of 0.4-1% of the population. It results in high healthcare costs and significant morbidity, especially for patients with severe symptoms. The RASTA-AF randomized control trial (RCT) is designed to answer the following question: does vigorous treatment of AF with …

18 years of age All Phase N/A
R Robert A McGovern

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains quite poor. This study uses wearable sensors to measure balance and uses deep brain stimulation electrodes to measure electric …

18 years of age All Phase N/A

Intimate Partner Violence Among People Who Inject Drugs - Prevalence, Risk Factors and Experiences

There are around 15,6 million people who inject drugs (PWID) worldwide, of which around 3,5 million are women who inject drugs (WWID) (1). In Sweden, estimates suggest 8000-21000 PWID (2). PWID are exposed to substantial health risks that are directly linked to injection drug use, such as blood borne viruses …

18 years of age All Phase N/A
S Shaolin Shen, PhD

Plasma Sphingolipid Metabolites and Radiotherapy Efficacy in Hepatocellular Carcinoma

Plasma contains a variety of metabolites, among which sphingolipids, including ceramide, sphingosine, and sphingosine-1-phosphate, serve as important intracellular second messengers and are involved in various cellular signaling pathways, such as apoptosis. We hypothesize that plasma sphingolipid levels may be associated with the efficacy of radiotherapy for liver cancer. This study …

18 - 80 years of age All Phase N/A
V Vincent Trebossen, Dr

Mixed-method Evaluation of a Parental Psychoeducation Programme in a Suicide Risk Prevention Group

The number of emergency consultations for children and adolescents for suicidal ideation and suicide attempts has been rising steadily since 2010, and even more so since 2020. In addition, 30% of children and adolescents who have committed a suicidal act reoffend within the year. Psycho-education programmes for patients have been …

18 years of age All Phase N/A
P Patrik Bachtiger

Hearables: Ear-ECG and PPG for Detection of Cardiac Arrhythmias

The goal of this observational study is to determine the feasibility of detecting abnormal heart rhythms, known as arrhythmias, by recording Electrocardiogram (ECG) and Photoplethysmogram (PPG) waveforms from the ears in patients who have already been diagnosed with arrhythmias. The main questions it aims to answer are: Can ECG and …

18 years of age All Phase N/A
S Sandrine Hegg-Deloye

Bone and Muscle Health Following Sleeve Gastrectomy in Men, Premenopausal and Postmenopausal Women

Background: Bariatric surgery is gaining in popularity. While it's health benefits are undisputed, the older malabsorptive bariatric procedures (Roux-in-Y gastric bypass - RYGB and biliopancreatic diversion - BPD) are associated with an increased risk of fractures and falls as early as 3-5 years after surgery. Sleeve gastrectomy - SG is …

18 years of age All Phase N/A
D Doaa Osman, Assis.prof

Pelvic Floor Dysfunction Among Female Physiotherapy Students: A Cross-Sectional Study

This study aims to: estimate the prevalence of pelvic floor dysfunction among female physiotherapy students at Cairo University. identify potential risk factors that may be associated with pelvic floor dysfunction in this student population. assess the level of awareness regarding pelvic floor health among female physiotherapy students at Cairo University. …

18 - 25 years of age Female Phase N/A

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