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Found 64,920 clinical trials
B Bing Zhang, MD, PhD

Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.

We are preparing to initiate a clinical trial involving Ferumoxytol for magnetic resonance-enhanced imaging in patients with atherosclerosis. The aim of this study is to assess the safety and effectiveness of Ferumoxytol for magnetic resonance angiography in patients with atherosclerosis.

18 years of age All Phase N/A
J Jianhua Ma, Professor

The Progress of Diabetes After Supaglutide Treatment in Type 2 Diabetes Patients

Glucagon like peptide-1 receptor agonist (GLP-1RA) can enhance insulin secretion and inhibit glucagon secretion in a glucose concentration dependent manner, delay gastric emptying, and reduce food intake through central appetite inhibition, thus achieving the effect of lowering glucose. Supaglutide Injection (YN-011, Diabegone®) has the characteristic of high affinity with GLP-1 …

18 - 75 years of age All Phase N/A
C Celia BASURKO, MD

Infant Feeding in French Guiana

This is a comparative, observal study among the population of pregant women who participated to the study "Nutri Pou Ti Moun" on food insecurity during pregnancy in French Guiana

years of age Female Phase N/A
D Dr Rajeev Khanna, MD

Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.

It is known that Immunosuppression post-Liver transplant is central to achieving optimal outcomes in liver transplant recipients. It is required to maintain an adequate balance between reducing rejection and toxicities. Mainstay drugs for maintenance therapy are Calcinuerin inhibitors - Tacrolimus versus cyclosporine. Tacrolimus is preferred, as it has less rejection …

- 18 years of age All Phase N/A
A Alexandre Baudet, Dr

Dental Emergencies Among Patients of the Health Care Access Center at the University Hospital of Nancy

The dental Health Care Access Center at the University Hospital of Nancy opened in January 2023. The patients ot the dental Health Care Access Center consulting the dental department have largely been treated as dental emergencies. However, to date, no study has been carried out into the nature of these …

years of age All Phase N/A
F Frankie Bennett, MS

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

Participants recruited for this study will be breast cancer or gynecological cancer patients who agree to participate in an exercise study examining the effects of chemotherapy on muscle mitochondrial oxidative capacity, a measure of skeletal muscle health. Participants will ride a stationary bicycle and the quadriceps muscle will be non-invasively …

20 years of age Female Phase N/A
L Lytfi Krasniqi, MD

Inflammation and Postoperative Atrial Fibrillation in Cardiac Surgery

Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, marked by an irregular and rapid heart rate, and associated with increased morbidity, longer hospital stays, and higher costs. Its complex pathophysiology involves atrial remodeling, inflammation, and autonomic dysregulation. Surgical trauma and cardiopulmonary bypass trigger an inflammatory response, releasing …

18 - 99 years of age All Phase N/A
J Jiuliang Yan, M.D.

A Clinical Study of Sorafenib Combined With Gefitinib for the Treatment of pNET

The incidence rate of pancreatic neuroendocrine neoplasms (pNENs) is increasing year by year. According to the statistical results of the SEER (Surveillance, Epidemiology, and End Results) database, the incidence rate of pNENs increased from 0.27/100000 to 1/100000 from 2000 to 2016, with a median overall survival time of 68 months. …

18 - 80 years of age All Phase N/A
Y Yu-qian Sun, M.D.

Clinical Registration Study of Haplo-HSCT for Elderly Patients With Acute Leukemia/ Myelodysplastic Syndrome

This study is an open, prospective, single-center, single-arm study expanded based on the study of NCT03412409.The primary objective of this study is to evaluate the transplantation efficacy of the RIC conditioning regimen in elderly patients receiving the transplantation of haploidentical hematopoietic stem cells. Elderly patients are defined as ≥55 years …

55 - 70 years of age All Phase N/A
G Ghanim Khatib, MD

Cukurova Score Validation Study

Despite significant advancements in imaging technologies, surgical techniques, chemotherapeutic regimens, and treatment strategies in recent years, ovarian cancer continues to remain the most deadly gynecological malignancy. Approximately 90% of ovarian cancers originate from the coelomic epithelium or modified mesothelial cells and are classified as epithelial ovarian cancers. The majority of …

18 - 100 years of age Female Phase N/A

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