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Found 64,783 clinical trials

The Importance of Inflammatory Markers Calculated From Preoperative and Postoperative Peripheral Blood Results in the Diagnosis and Treatment of Patients Operated for Hydatid Cyst of the Lung (Lung Echinococcus Granulosus)

This study aims to investigate the role of these laboratory findings in the differential diagnosis and management of pulmonary hydatid cyst (PHC) by examining the number of euzonophils, neutrophils, lymphocytes, platelets and neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic immune inflammatory index values in the peripheral blood of patients diagnosed with …

18 - 83 years of age All Phase N/A
E Erica Morse, MA

Collaborative Care for Treatment of Depression and Anxiety

The goal of this project is to evaluate the effectiveness of a collaborative care model for primary care patients at Kaiser Permanente Colorado (KPCO) with depression and/or anxiety. Collaborative care uses evidence-based short-term treatments delivered to patients over the phone. We will explore the use of cost-efficient automated processes for …

18 years of age All Phase N/A
R Rickard Zeijlon, M.D. PhD

Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital

The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these patients. The main questions it aims to answer are: What is cumulative incidence of Takotsubo-stunning in patients hospitalized for …

18 years of age All Phase N/A
F Fengyan Jin, Professor

A Perspective Study of the MRD-tailored Therapy in Patients With Newly Diagnosed Multiple Myeloma With Persistent Minimal Residual Disease After Initial Treatment

The aim of this study was to observe the rate of MRD conversion and the impact on survival in newly diagnosed multiple myeloma (NDMM) patients with persistent MRD positivity after induction and consolidation therapy (autologous hematopoietic stem cell transplantation or consolidation of the original regimen) who were switched to high-intensity …

18 years of age All Phase N/A
N Nicholas J Larson

Utilizing 3D Imaging for Burn Wound Assessment

The goal of this prospective cohort study is to determine if the DermaMonitor camera can accurately determine burn size in patients with 1st, 2nd, or 3rd degree burns, with exploratory aim of testing a new Artificial Intelligence (AI) program for determining burn depth. The main aims are: The primary aim …

18 - 89 years of age All Phase N/A
K King's Ophthalmology Research Unit

Prospective Ocular Imaging for Intracranial Pressure Evaluation

This is a prospectively recruiting, database development study collecting images and videos of the spontaneous venous pulsation at the back of people's eyes - this is a pulse one can see on examination of the back of the eye, originating from the blood vessels around the nerve that connects the …

18 years of age All Phase N/A
W Wietse Claeys, MD

Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender Persons

This study aims to explore sexual satisfaction among transgender men and their partners following the placement of erectile prostheses after phalloplasty. While phalloplasty can create a neophallus, the lack of natural erectile tissue often necessitates the use of erectile aids, including internal prostheses. However, these prostheses, originally designed for cisgender …

18 years of age Female Phase N/A
B Betul Cinar

Turkish Version of Pelvi-Perineal Surgery Sexuality Questionnaire

This prospective, multicentre observational study translates the 13-item Pelvi-Perineal Surgery Sexuality Questionnaire (PPSSQ) from French to Turkish, culturally adapts it, and evaluates its reliability, validity and responsiveness in Turkish-speaking women covering from pelvic floor surgery.

18 - 65 years of age Female Phase N/A
B Bin Cheng, Professor

Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor Diagnosis

This study develops a multimodal AI model using endoscopic ultrasound, white-light endoscopy, and clinical information to support the diagnosis of upper GI mesenchymal tumors and the risk stratification of gastric GISTs.

18 years of age All Phase N/A

Myocardial Work Evaluation in Patients With PAH

Right ventricular function is a key determinant of survival in patients with pulmonary arterial hypertension, with right heart failure being the leading cause of death. ERS/ESC guidelines recommend evaluating RV function at diagnosis and at first reevaluation under treatment to estimate the one-year mortality risk. However, few RV function markers …

19 years of age All Phase N/A

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