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Found 64,783 clinical trials
M Michelle Science

Viral Dynamics and Transmission of Influenza, RSV and SARS-CoV-2 in Children

Viral respiratory tract infections are very common in children. They contribute to missed time in school, work disruption for caregivers and can also cause severe illness requiring hospitalization and rarely death. In the 2022-2023, influenza, RSV and SARS-CoV-2 viruses infected a large number of children which strained the pediatric healthcare …

1 years of age All Phase N/A
K Karin GF Gerritsen, MD, PhD

Study to Examine the Effect of the Diuretic Furosemide on the Plasma Levels of Toxins and the Removal of Toxins from the Blood in Patients with Chronic Kidney Disease

The goal of this observational study is to examine the interaction between the diuretic furosemide and certain toxins called protein-bound uremic toxins (PBUTs) in patients with chronic kidney disease (CKD). The main question it aims to answer is: what is the effect of furosemide on plasma levels of PBUTs in …

18 years of age All Phase N/A
A Ahmad HAYEK, MD

Identifying Biological Markers of Cardiovascular Events in Patients With Aortic Stenosis or TAVI

Aortic stenosis, a common cardiovascular disease, is pathophysiologically associated with a chronic inflammatory myocardial reaction and fibrosis leading to cardiac dysfunction and impaired coronary perfusion. These elements may precede the onset of symptoms. The assessment of inflammatory and fibrosis factors (in particular by means of biomarkers) in patients with aortic …

18 years of age All Phase N/A
S Sophie BONNIN, PH

Functional and Anatomical Visual Investigations in Patients With Early Forms of Age-related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of visual impairment in industrialized countries. Anatomical examination findings at the early and intermediate stages of AMD are not sufficient to determine any functional alterations at these stages (e.g., alterations in microperimetry, multifocal electroretinogram (mfERG) and contrast sensitivity). Identifying early functional markers …

18 years of age All Phase N/A
Y Yael Sarig, B.A.

External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

This is a pilot study (small-scale study) that aims to understand more about how blood flow changes in people who have low blood sugar after bariatric surgery (post-bariatric hypoglycemia) compared to those who have had surgery without hypoglycemia, those who have hypoglycemia without surgery, or those who do not experience …

18 - 70 years of age All Phase N/A
A Ahmed A Zahra, MD

Added Value of Ultrasonography in the Diagnosis, Management, and Follow-Up of Carpal Tunnel Syndrome

This study aims to assess the ultrasound (US) and nerve conduction studies (NCS) as a tool for diagnosis, treatment planning and follow-up of patients with carpal tunnel syndrome (CTS).

18 years of age All Phase N/A
R Rajeev Garg, MD

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are …

18 - 80 years of age All Phase N/A
D Dongling Zou, M.D.

Artificial Intelligence Model for Growth Prediction of Ovarian Cancer Organoids

The present study aims to collect early bright field image of patient-derived organoids with ovarian cancer. By leveraging artificial intelligence, this study will seek to construct and refine algorithms that able to predict growth of ovarian cancer organoids.

years of age Female Phase N/A
P Pietro Bertoglio, MD

Use of a Smartphone APP for the Management of Postoperative Home Recovery

To calculate the incidence rates of postoperative adverse events (moderate and severe) and rehospitalization in patients undergoing thoracic surgery followed in follow-up using a smartphone application.

18 years of age All Phase N/A
M Manon TESSIER

Study of the Prevalence of Pediatric Eating Disorders in Inherited Metabolic Diseases with Dietary Treatment

The main objective of this study is to estimate the prevalence of Pediatric Eating Disorders (PED) in Inherited Metabolic Diseases (IMD) with dietary treatment between the age of 12 months and 6 years 11 months.

12 - 6 years of age All Phase N/A

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