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Found 64,920 clinical trials
P Pascale Grzonka, MD

Pupillometric Evaluation in Patients Declared Brain Dead - a Prospective Quality Control Study

The aim of the study is to verify the reliability of the current purely clinical examination of the pupils (without the support of a pupillometer) in the context of clinically suspected brain death, compared to the results of a non-invasive, automated, and highly precise monocular pupillometric examination.

18 years of age All Phase N/A
S Shengwen Yang, Ph.D MD

FAPI Imaging Assessment of Chronic Total Occlusion

This registry will include consecutive patients presenting with at least one chronic total coronary occlusion (CTO) identified via coronary angiography or cardiac computed tomography angiography (CCTA) at our center. Due to the complexity of CTO lesions, both procedural success rates and prognosis improvements are limited. The progression and development of …

18 years of age All Phase N/A
K Kedir N Tukeni, MD, Internist, cardiologist

Sepsis and Myocarditis

This prospective cohort study aims to investigate the cardiac manifestations of sepsis and their influence on disease outcomes among adult patients at Jimma University Medical Center, Ethiopia, from May 2025 to May 2026. The research will include adults aged 18 and older with sepsis, categorizing them based on the presence …

18 years of age All Phase N/A
I Iris Simons, MD

P4O2 ILD Extension

The goal of this observational study is to identify early biomarkers that can predict the development of progressive pulmonary fibrosis (PPF) in participants with interstitial lung diseases (ILDs). The participant population includes adults diagnosed with idiopathic pulmonary fibrosis (IPF), familial pulmonary fibrosis (FPF), other fibrotic ILDs, and interstitial lung abnormalities …

18 - 80 years of age All Phase N/A

GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms

This is a GWAS that aims to identify possible single nucleotide polymorphisms (SNPs) that are associated with the response in a combined dietary pattern low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols and Meditteranean diet (MED-LFD) in a small group of patients with Irritable Bowel Syndrome (IBS).

18 - 65 years of age All Phase N/A
J JEAN-PHILIPPE CAMDESSANCHE, PHD

Genotype/Phenotype Correlation of MORC2 Mutations

The Microrchidia CW-type zinc finger 2 (MORC2) gene encodes a protein expressed in all tissues and enriched in the brain. It is involved in Charcot-Marie-Tooth disease, with mire than 30 families presenting MORC2 mutations. Recently, MORC2 mutation have been shown to be responsible for more complex phenotypes like DIFGAN: developmental …

4 years of age All Phase N/A
K Khaled A Elsayed, Specialist

Colorectal Cancers :A Retrospective Study

Clinico-epidemiological and endoscopic characteristics of patients with colorectal cancers:A Retrospective study in Sohag The aim : determine the prevalence and clinicopathological pattern of patients with colorectal cancers interpretative association between risk factors and severity of patient condition to define possible predictors assess potential association between serum markers, imaging, endoscopic features …

18 - 80 years of age All Phase N/A

Relation Between Bone Mineral Density, Gross Motor Function and Quality of Life In Children With Cerebral Palsy

studying the relationship between Bone Mineral Density, Gross Motor Function and, Quality of Life with CP can provide valuable insights into the musculoskeletal consequences of motor impairments and guide interventions to improve bone health. Statement of the problem Is there a relation between Bone Mineral Density, Gross Motor Function and …

7 - 10 years of age All Phase N/A
H Heather Brooks

Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment

The goal of this observational study is to validate the Creyos online cognitive assessment platform in individuals with mild cognitive impairment, or remitted major depressive disorder. The main objectives of this research are: To confirm the feasibility of administering the Creyos cognitive battery to older adults with Mild Cognitive Impairment …

60 years of age All Phase N/A
I In Joon Lee, MD, PhD

Same-day Radioembolization for Large HCC

In patients who has no sign suggesting high lung shunt fraction (TIPS, hepatic vein invasion, hepatic vein enhancement on arterial phase, dysmorphic intratumoral vessel), planning angiography, MAA scan, and radioembolization are performed in a single day with SIR-Spheres. This prospective registry will prove that the selection criteria is accurate and …

19 years of age All Phase N/A

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