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Found 65,447 clinical trials

A Non-interventional, Prospective Study With Benralizumab

This is a prospective, non-interventional, single-arm, multicenter study to investigate asthma control, and health-related quality of life (HRQL), lung function and asthma medication intake in severe eosinophilic asthma patients treated with benralizumab in a real-life setting in Germany.

18 - 120 years of age All Phase N/A
V Virgini Van Buggenhout

Holmium-166 Transarterial Radioembolization for the Treatment of Hepatocellular Carcinoma

This study aims to evaluate the effectiveness and safety of Holmium-166 (Ho-166) transarterial radioembolization (TARE) for treating patients with locally advanced hepatocellular carcinoma (HCC), a common type of liver cancer. HCC is often linked to conditions like liver cirrhosis and viral hepatitis, with a poor prognosis for advanced stages. TARE …

18 years of age All Phase N/A
Y Yun Tian, M.D

The Construction of Bidirectional Column Study of Acute Osteoporotic Vertebral Compression Fractures

Our research group plans to establish a disease specific bidirectional cohort study on prognosis prediction of acute osteoporotic vertebral compression fracture based on imaging and clinical data, and to establish a comprehensive bioinformation database on OVCFs, including patient status, clinical data, laboratory examination, and imaging examination database

50 - 100 years of age All Phase N/A
A Abdelrahaman Abdallah

The Role of Angiojet Rheolytic Thrombectomy in The Management of Iliofemoral Deep Venous Thrombosis

The aim of this study is to evaluate the efficacy and safety of rheolytic thrombectomy in restoring venous patency DVT, periprocedural complications and development of PTS after tratment of iliofemoral DVT.

18 - 60 years of age All Phase N/A
M Matthieu Legrand, M.D., Ph.D

Role of Transposable Elements in Septic Immune Aging

The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: Do transposable elements prematurely age the immune systems of patients with sepsis? Do transposable elements correlate with increased mortality in patients with …

18 years of age All Phase N/A
M Mohamed Fekry, Lecturer

Pulmonary Artery Doppler in Preeclamptic Mothers

Evaluation of Pulmonary artery Doppler parameters in fetuses of mothers with severe preeclampsia

years of age Female Phase N/A
M Muriel Fartoukh, PU-PH

Prevalence, Determinants and Consequences of Dyspnea During Weaning in Critically Ill Obese Patients

ICU patients encounter numerous discomforts, with dyspnea (the sensation of breathlessness) being among the most distressing and impactful. Unlike pain, dyspnea in ICU settings has historically received limited attention, despite its severe psychological impact. ICU clinicians often use assessment tools like the simple numerical dyspnea scale (Dyspnea-VAS) and the Respiratory …

18 years of age All Phase N/A
A Aaron Bartoe, DO, MS

Droperidol and QTc Interval Changes in ED Patients

Objectives To assess the association of low-dose Droperidol administration in the emergency department with changes in the QTc interval. Hypothesis Our study is designed to test the null hypothesis that there will be no clinically significant change in QTc interval after administration of 2.5mg of IV Droperidol during an emergency …

18 years of age All Phase N/A
D Daniel L Piskorz, MD

Subclinical Atrial Fibrillation Home Monitoring in Hypertensive Patients

Atrial fibrillation is a highly prevalent and incidental arrhythmia, often asymptomatic, and frequently detected incidentally or in association with a stroke. Subclinical atrial fibrillation increases cardioembolic risk, highlighting the need for timely diagnosis. New wireless devices capable of recording heart rhythm, combined with innovative artificial intelligence tools, could be useful …

65 years of age All Phase N/A
Y Yao Zhu

Novel Therapy Target in Metastatic Prostate Cancer

The aim of this study is to use multiomics sequencing to explore the molecular characteristics of metastatic prostate cancer (mPCa), especially metastatic castration-resistant prostate cancer (mCRPC). At the same time, mCRPC models will be constructed, including organoids and animal models, serving as a basic and translational research platform to help …

18 years of age Male Phase N/A

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