Found 64,783 clinical trials
Four Cycles Taxane With Trastuzumab and Pertuzumab Neoadjuvant Therapy Among Low Risk HER2 Positive Patients
Neoadjuvant therapy in the treatment of breast cancer is not only a means of breast conserving surgery, but also a sensitive scheme for patients, in order to reduce the treatment grade, low toxicity and high efficiency. Chemotherapy combined with trastuzumab and pertuzumab is the standard neoadjuvant therapy for HER2 positive …
Aspirin and Neutrophils in Preeclampsia
The exact mechanisms by which aspirin prevents the development of preeclampsia in high-risk patients are currently not fully known. Furthermore, a small proportion of high-risk patients who are on low-dose aspirin (LDA) still go on to develop preeclampsia (PE). This longitudinal observational study will assess the immune profile in participants …
A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis
This study evaluates whether a special type of blood analysis, called liquid biopsy (LBx), correlates with mammography results and/or diagnosis of breast cancer.
Dinutuximab Beta at the HUS and the Toulouse Oncopole
In this study the investigators wish to describe the cohort of pediatric patients suffering from neuroblastoma and treated with Dinutuximab and to compare the costs and quality of life between the two French centers, the University Hospital of Strasbourg (HUS) and the Oncopole of Toulouse.
Health Literacy of Parents Regarding Neonatal Jaundice
This study will be conducted as a relational descriptive study to determine the health literacy level of parents with infants between 0-28 days of age regarding neonatal jaundice. The secondary aim of the study is to examine whether the health literacy levels of the parents differ with parent and infant …
Biochemical and Histological Changes in Pregnant Women With Preterm Premature Rupture of Membrane
Although preterm premature rupture of membranes (PPROM) is one of the most common causes of preterm birth, it can also lead to serious maternal and neonatal complications. Although there are many known risk factors, the cause is not fully understood . Proteoglycans (PG) are macromolecules containing a core protein and …
Predictors of Relapse in Major Depressive Disorder
Major depressive disorder (MDD) is a common condition involving recurring periods of depression. One of the major challenges faced by people with MDD is that the episodes of depression tend to recur even after they are successfully treated. Currently, it is hard to predict when a depressive episode will recur. …
Smartphone Addiction in University Students
Smartphone usage has increased significantly in the last decade and smartphones have changed our lives to a great extent. Smartphone usage has advantages as well as disadvantages and therefore brings phone addiction with it. Smartphone addiction is defined as excessive use of smartphones to the extent that it disturbs the …
Influence of Protein Intake on Muscle Mass and Health-related Quality of Life During and After Radiotherapy
The influence of radiotherapy on the protein intake and muscle mass of patients has not been extensively investigated to date. It is also unclear whether the localization of the tumor disease and thus the radiation field have different effects. Therefore, with the pilot study presented here, we would like to …
Correlation Analysis of POD and pNCD in Elderly Patients With Gastrointestinal Neoplasms
This is a prospective cohort study to explore the differences of serum indicators between elderly gastrointestinal neoplasms patients with postoperative delirium (POD) who either develop or do not develop long-term postoperative neurocognitive disorders (pNCD).
