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Found 64,920 clinical trials
C Ciro Cabezas Checchi, MD

Dietary Factors Associated to Colorectal Premalignant Lesions (COLOMAR-1)

This study aims to find a correlation between fish protein intake and other dietary habits and colorectal premalignant lesions in healthy volunteers. It also aims to describe gut microbial profiles for each dietary pattern, in order to elucidate the role of fish intake in cancer prevention.

45 years of age All Phase N/A
J Judit Varkonyi-Sepp, Chief Investigator

LIving BEtteR With asThma - Intervention Development Study

Approximately 330 million people in the world are living with asthma and 3-10% of them has difficult asthma that is challenging to control even with maximum doses of pharmacological treatment. In the last five years our multidisciplinary team has shown the clinical benefits of a short-term structured exercise programme for …

18 years of age All Phase N/A
S Susanne Leij

QoL in OSA patiënts Treated With MMA Surgery.

The aim of this observational study is to evaluate the impact of maxillomandibular advancement surgery on the quality of life in patients treated with obstructive sleep apnea. The main question it aims to answer is: Does MMA surgery in OSA patiënts improve their quality of life? Patients will answer online …

18 years of age All Phase N/A
P Patrick R Noerhave, MD

Circulating Tumor DNA in Peripheral T-cell Lymphomas

The aim of this study is to evaluate the feasibility of circulating tumor DNA (ctDNA) measurement in blood plasma for the applicability in prognostication, treatment evaluation and measurable residual disease (MRD) surveillance in a cohort of patients with newly diagnosed or relapsed/refractory peripheral T-cell lymphomas (PTCL).

18 years of age All Phase N/A
A Ann Hallemans, PhD

Gait and Postural Balance Analysis During Head-motion Perturbed Standing and Walking in Older Adults

The main aim of this study is to unravel the biomechanics of postural balance reactions during head-motion perturbed standing and walking in older adults who fall, while integrating the influence of frailty, sensory functioning and cognitive processing.

65 - 100 years of age All Phase N/A
A Anoop Misra, MD

Comparison of Micro- and Macrovascular Disease(s) in People With T2D, Who Have Moderate to Severe Acanthosis Nigricans vs. Those Who do Not Have Acanthosis Nigricans

Hypothesis: Moderate to severe acanthosis nigricans in people with T2D is associated with higher magnitude of complication than people who do not have acanthosis nigricans. Objectives: To correlate moderate to severe acanthosis nigricans with diabetes complication Methodology T2DM patient will be recruited from endocrine OPD Clinical History and Examination: General …

20 - 70 years of age All Phase N/A
L Laurent MD MELY

Muscle Function and Physical Activity in the Modern Era of Cystic Fibrosis

Cystic fibrosis (CF) is characterized by various extrapulmonary manifestations, including altered skeletal muscle function, with both quantitative (e.g. reduced muscle mass) and qualitative (e.g. impaired oxidative function) impairments that may have a negative impact on exercise tolerance and quality of life. These abnormalities have traditionally been related to disease (e.g. …

10 years of age All Phase N/A
Z Zhengfei Zhu, MD

Neuroendocrine Transformation in RB1/TP53 Inactivated NSCLC

Histology transformation from non-small cell lung cancer (NSCLC) to neuroendocrine carcinomas (NEC), especially from epidermal growth factor receptor (EGFR) mutant lung adenocarcinoma (LADC) to small cell lung cancer (SCLC), is widely recognized as a rare mechanism for NSCLC to confer tyrosine kinase inhibitors (TKIs) resistance. The probability of its occurrence …

18 years of age All Phase N/A
J Joaquim Bellmunt, MD, PhD

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

The goal of this study is to better understand how to best treat participants with advanced bladder cancer who may not be able to tolerate all of the chemotherapy drugs that have been shown to be effective. In this study, investigators are assessing the role of the survey, the Geriatric-8, …

65 years of age All Phase N/A
M Marika Pane, prof

phenotypeS in Non Ambulant Duchenne Muscular Dystrophy

The aims of the study are to prospectively collect information on several aspects of function in non-ambulant DMD patients by using a structured battery of tests including motor, respiratory and cardiac function

8 - 35 years of age Male Phase N/A

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