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Found 638 clinical trials
D Despoina Liotiri, Consultant

Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes

The purpose of this study is to evaluate the impact of compliance with enhanced recovery after surgery (ERAS) program on patient reported outcomes (PROs), surgery-specific outcomes and stress response after pancreatic surgery. This prospective observational study will include all consecutive patients undergoing pancreatic surgery over a period of three years …

18 years of age All Phase N/A
P Phu Lam

Pilot Study of Pancreatic Cancer Screening

This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening …

18 years of age All Phase N/A
P Patrick J. Worth

Use Of Indocyanine Green In Pancreas Surgery

This study evaluates the use of indocyanine green to predict postoperative pancreatic leaks in patients undergoing transection of the pancreas.

18 years of age All Phase N/A
A Anthony Maraveyas

Tumour Regulatory Molecules in Early Pancreatic Cancer Detection

The effective diagnosis of pancreatic cancer is often quite challenging, due to a lack of disease-specific symptoms, resulting in the majority of patients presenting with advanced disease, with an associated dismal prognosis. Earlier detection of pancreatic cancer, at a stage where surgery is feasible, would greatly increase the 5-year survival …

18 years of age All Phase N/A
Z Zhuo Cheng, M.D.

Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE)

Biliary stricture is mainly malignant in the adults and caused by several types of fatal malignancies such as pancreatic cancer, cholangiocarcinoma, and metastatic tumor, which have poor prognosis that the overall survival of unresectable lesions is no more than 15 months. The poor outcome often relates to a lack of …

18 - 85 years of age All Phase N/A
B Barbara J Broome

Artificial Intelligence in Endoscopic Ultrasound

The objective of the study is to determine if this artificial intelligence system is capable of detecting abnormalities in the pancreas that are identified by an endoscopist at endoscopic ultrasound procedures.

18 - 100 years of age All Phase N/A
D Duowu Zou, MD

The Characteristics of Oral Microbiota in Chronic Pancreatitis and Autoimmune Pancreatitis

There are more than 700 different bacteria colonized in human oral cavity, which are collectively referred to as oral microbiota. Emerging evidence suggests that oral microbiota plays a series of important roles in human health, such as immune response, carcinogen metabolism and nutrient digestion. The changes of oral microbiota composition …

18 years of age All Phase N/A
G Giovanni Trovato, MD

Prospective Single-center Study About the Use of ctDNA in the Management of Patients With Tumors of the Gastrointestinal Tract

This study will evaluate the use of ctDNA in the clinical management of patients with tumors of the gastrointestinal tract.

18 - 85 years of age All Phase N/A
E Elias khajeh, Dr.

Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON Endostapler

This prospective, observational study evaluates the rate of postoperative pancreatic fistula (POPF) following distal pancreatectomy (DP) using the AEON™ Endostapler. The study involves 110 patients undergoing DP and assesses primary outcomes based on the International Study Group of Pancreatic Fistula (ISGPF) classification, alongside secondary perioperative parameters. The findings aim to …

18 years of age All Phase N/A
D Dale Palmer

Characteristics of Intestinal Microbiome Following Pancreatic Surgery

The goal of this observational study is to learn about intestinal microbiome structure and function in individuals who have undergone a pancreatoduodenectomy and compare to healthy matched controls. The primary objectives of the study are: To explore and describe any differences in the gut microbiota especially Shannon diversity index To …

18 years of age All Phase N/A

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