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Found 64,920 clinical trials
J Jingyyuan Xu, MD

Prognostic Value of PtcO2 in Patients With COVID-19

Five percent of patients with COVID-19 progressed to respiratory failure and required ICU admission, such patients often have abnormal oxygen tolerance. However, there is still a lack of clinical indicators to predict the prognosis and treatment responsiveness of COVID-19.

18 - 80 years of age All Phase N/A

Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).

18 years of age All Phase N/A
B Bert Houben

Multicenter Ventral Mesh Rectopexy Registry Collaborative

The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal prolapse or combined) by laparoscopy or robotic surgery and to evaluate the longterm functional outcomes. Secondly complications (mesh erosions, recurrence, reoperations) …

18 years of age All Phase N/A
J Jana Fox

Intra-Operative Radiation Registry

This registry trial is designed to track the local control rates and side effects of IORT, which will be implemented for women who are suitable PBI per the latest ASTRO guidelines.

18 years of age Female Phase N/A
J James Burton, FRCP

Validating Novel, Non-contrast Cardiac MRI Imaging in Haemodialysis Patients

There are currently no good ways of measuring levels of scarring in the hearts of patients with advanced kidney disease and patients on dialysis, although recent research has shown a new cardiac MRI technique, called native T1 mapping, may provide a solution to this. To assess the accuracy of this …

18 years of age All Phase N/A
K Karin Ljung, PhD

Biological Mechanisms Behind Resynchronization Therapy in Heart Failure

Heart failure is a common disease, affecting 2-3% of the population in the western world. About 30% of patients with heart failure and reduced ejection fraction display signs of electrical dyssynchrony on ECG, usually left bundle branch block (LBBB), which is associated with a worse prognosis. Cardiac resynchronization therapy (CRT) …

18 - 80 years of age All Phase N/A
G Gonzalo Quaino

Safety and Efficacy Evaluation of Orbital Atherectomy System in de Novo Calcified Lesions

This is a French, prospective, single-arm, multi-center registry to confirm the safety and efficacy of the Diamondback 360 TM Orbital Atherectomy System in the preparation of de novo calcified coronary lesions before implantation of a coronary endoprothesis in adult subjects. The primary safety endpoint is 30-day MACE and the efficacy …

18 years of age All Phase N/A
F Frank Willeke, MD

The TransEnterix European Patient Registry

An open label observational registry trial in which participating centers enroll subjects who had or will have a laparoscopically assisted surgery using the Senhance Surgical System.

18 - 80 years of age All Phase N/A
K Koichi Yuki, MD

Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood …

2 - 50 years of age All Phase N/A

Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels

Acute normovolemic hemodilution (ANH) is performed as a blood conservation technique during surgical procedures with high risk for significant blood loss. It is done by taking out some of the patients blood before surgery actually begins and storing this blood inside of the operating room and giving it back to …

18 - 70 years of age All Phase N/A

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