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Found 64,920 clinical trials
L Loïc Garcon

Immunophenotyping of Blood Cells in the Diagnosis Work-up of Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematological malignancies characterized by cytopenia(s), dysplasia in one or more major myeloid cell lines and progression to acute leukemia. Morphological analysis of peripheral blood (PB) and bone marrow (BM) remains the cornerstone of the diagnosis. Preliminary studies identified Flow Cytometry (FC) markers …

18 years of age All Phase N/A
Q Qian Qi, Doctor

Characteristics of Hospitalized Patients With Community-acquired Pneumonia

At present, the epidemiological characteristics and the distribution of pathogens of community-acquired pneumonia in Shandong Province are not clear. In order to understand the characteristics of community-acquired pneumonia, the distribution of pathogens and the risk factors of complications in Shandong Province, it is necessary to carry out investigation and study, …

14 years of age All Phase N/A
Y Yan Liu

Risk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic Diseases

With the development of China's economy, people's living standard have improved, and the dietary structure have changed. Metabolic diseases, such as hypertension, diabetes, hyperuricemia and obesity have gradually become an important health burden in China. The pathophysiological mechanism of renal injury caused by metabolic diseases has always been a hotspot …

18 - 80 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Tumor Related Epilepsy

Background Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems. Researchers think this may improve the outcome for people with brain tumors. It may completely …

8 - 99 years of age All Phase N/A
S Steven E Wolf, MD

Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology

The purpose of this investigation is to better understand the wound microbiome in burn wounds and the role it plays in outcomes and complications related to treatment.

18 - 100 years of age All Phase N/A

Open Nipple Sparing Mastectomy (NSM)

This is retrospective, multicenter chart review is to evaluate the complication rates of prophylactic open NSM procedures through 42 days postoperatively

18 years of age Female Phase N/A
M Matthieu Roustit

Application for Monitoring and Evaluation of Raynaud's Phenomenon

To evaluate the feasibility of using a smartphone application for monitoring and evaluation of Raynaud's Phenomenon.

18 - 75 years of age All Phase N/A
C Caitlin Guzowski, MBA, MHA

Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation

This trial will evaluate the safety and efficacy of RIC HIDT transplant protocol following fludarabine and intermediate-dose TBI 800 cGy utilizing PBSC as the stem cell source.

18 years of age All Phase N/A
M Mikael AGOPIANTZ, PHD MCU

The Determinants of Fertility Preservation in TRANSgender Patients.

The study is monocentric, retrospective, non-interventional and does not involve human subjects. The main objective is to compare the profiles of transgender patients who undergo fertility preservation with those who do not. The secondary objectives are to define the rate of recourse to fertility preservation, determine the proportion of patients …

18 - 60 years of age All Phase N/A

Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery

The objective of this study is to collect in a prospective registry all cases of French patients undergoing an assessment for percutaneous treatment of mitral valve disease on a native valve or due to deterioration after surgical valve repair or replacement. In these patients, valvular surgery should be considered contra-indicated …

18 years of age All Phase N/A

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