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Found 64,783 clinical trials

Antifungal Agents and Infrared Thermotherapy Alone or in Combination in the Treatment of Sporotrichosis

Sporotrichosis is a chronic granulomatous mycosis caused by sporothrix complex. The course of sporotrichosis is always prolonged and even life-threatening, the treatment of this disease in an important scientific problem to be solved. The investigators previously found the predominance of subtype M2 macrophage which play an anti-inflammatory role in the …

years of age All Phase N/A
D DAJIN KIM

To Evaluate the Safety, Pharmacokinetic Characteristics and the Effect of Food After Administration of JLP-2004

To evaluate the safety, pharmacokinetic characteristics and the effect of food after administration of JLP-2004

19 years of age All Phase 1
V Vitaliana R Vasquez, BA

Computational Assessment of GABA Receptor Modulation in PTSD

A substantial majority of Veterans with posttraumatic stress disorder (PTSD) continue to suffer even with the best current medications. Progress in developing more effective medications is hampered by the substantial variability within Veterans with PTSD, meaning the most effective medication likely varies from individual to individual. New scientific tools to …

18 - 65 years of age All Phase 4
J Ja-Ho Leigh

Driving Ability Evaluation System to Improve the Conditional Driving License System: Safety and Feasibility Study.

The primary objective of this study is to verify the safety and validity of a VR driving simulator developed for evaluating the driving abilities in healthy adults. This study also aims to establish indicators in VR driving simulator to evaluate high-risk group for driving, such as cognitive and physical abilities. …

19 - 65 years of age All Phase N/A
M Marion Brands, MD

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

A pivotal, randomized, double-blind, placebo controlled, multi-center therapeutic study for patients age 4 and older with a confirmed diagnosis of Niemann Pick disease type C (NPC). The objective of this study is to evaluate the safety, tolerability and efficacy of N-acetyl-L-leucine (IB1001) compared to standard of care. Following this randomized, …

4 years of age All Phase 3
Y Yi-Cheng Zhang

A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 )

A Clinical Study to Investigate the Safety, Efficacy, and Cellular Metabolism of CT1190B CAR-T Cell therapy, in Patients with Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma.

18 - 75 years of age All Phase 1
E Edílson S Cyrino, PhD

Effect of Two Years of Resistance Training on Health Status in Postmenopausal Women: Longitudinal Study Active Aging.

Aging is a natural process of the life cycle that can result in morphological, neuromuscular, metabolic, physiological, cognitive and behavioral changes that can compromise quality of life, autonomy, self-esteem, health and life expectancy, especially in the elderly. On the other hand, resistance training (RT) has been widely recommended for the …

60 years of age Female Phase N/A
R Richard Paulson, MD

Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation

The goal of this clinical trial is to evaluate a long Clomid protocol as compared to a 5-day Clomid protocol for ovarian stimulation in patients with diminished ovarian reserve undergoing ovarian stimulation for in-vitro fertilization. The aim of the long Clomid protocol is to intensify stimulation of the ovaries and …

18 - 45 years of age Female Phase 4
L Leidy Johanna Rueda Díaz Leidy Johanna, PhD

Bird Watching to Reduce Stress in University Students

The goal of this study is to learn if birdwatching can reduce stress in university students. It will also explore students; experiences with the intervention. The main questions it aims to answer are: Does birdwatching reduce students perceived stress levels? What are the experiences of students who participate in the …

18 - 100 years of age All Phase N/A
A Alberto Benussi, MD

At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that causes gradual muscle weakness and loss of muscle mass. It affects all muscles that control movement, speech, swallowing, and breathing. Unfortunately, ALS is currently incurable, and treatments are limited. Only two medications, riluzole and edaravone, have been approved and can …

18 years of age All Phase N/A

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