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Found 64,783 clinical trials
M Mette tranberg Nielsen, phd

Screening Triage and Risk Stratification

To investigate the performance of cytology, extended genotyping, p16/Ki67 dual stain cytology, DNA methylation and viral load as triage markers in post-menopausal HPV-screen-positive women aged 50-64 years in the organized screening program to predict the risk of developing CIN2+. (work package 1) To investigate the performance of cytology, extended genotyping, …

23 - 64 years of age Female Phase N/A
H Ho-Il Yoon, M.D.

Seoul National University Airway Registry

This is a multicenter, prospective observational cohort study, in which patients with chronic airway diseases including chronic obstructive pulmonary disease(COPD), asthma, asthma-COPD overlap syndrome (ACOS) will be recruited.

20 - 90 years of age All Phase N/A
A Adetunji T Toriola, M.D., Ph.D., MPH

ColoCare Study - Colorectal Cancer Cohort

ColoCare is an international prospective cohort study of stage I-IV colorectal cancer patients (ICD-10 C18-C20).

18 - 89 years of age All Phase N/A
G Gengru Jiang, MD

Genotype-Phenotype Correlations in Patients With Alport Syndrome

Alport syndrome (AS) is caused by pathogenic variants in the type IV collagen genes COL4A3, COL4A4, and COL4A5. This study aims to enroll families and patients with a history of renal hematuria in 27 hospitals and detect these three genes for AS screening. This study also aims to analysis the …

years of age All Phase N/A
J Jacob Holmqvist, MD

Acute Cardiac Dysfunction in Critical Illnes

The overall aim of the study is to establish the clinical importance of cardiac dysfunction, by estimating its incidence and impact on short- and long-term outcomes, in a mixed population of critically ill patients with multi-organ failure. Pathogenesis of cardiac dysfunction in critical illness and key molecules linked to this …

18 years of age All Phase N/A
R Randall E Brand, MD

Pancreatic Adenocarcinoma Gene Environment Risk Study

After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants …

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

Background The immune system is made up of special cells, tissues, and organs that fight infections. Problems with this system may lead to frequent, severe, or unusual fungal infections. These infections are often difficult to treat. Researchers want to collect blood and tissue samples from people who have unusual, persistent …

1 - 99 years of age All Phase N/A
Y Yinyin Zang

Children to Adults Mental and Psychosomatic Health Study (CAMPS)

This study titled the Children to Adults Mental and Psychosomatic Health Study (CAMPS), aims to explore the interplay between mental health, psychosomatic factors, and adverse childhood experiences (ACE) across a broad age range, from school-age children to adults in China. The study will involve participants from various educational settings, including …

9 - 65 years of age All Phase N/A
A Antoine Deschildre, MD

Consequences of COVID 19 Pandemic on Childhood Asthma

The SARS-CoV2 pandemic, which emerged in the first quarter of 2020, has led to an unprecedented health crisis in our modern healthcare systems and has resulted in strong national public health measures. The impact of the pandemic and its indirect environmental consequences on pediatric asthma is currently being assessed. In …

3 - 16 years of age All Phase N/A
L Linlin Wang

Real-World Study of Iruplinalkib in the Treatment of ALK-Positive Non-Small Cell Lung Cancer

This study is a national multicenter real-world investigation aimed at evaluating the real-world effectiveness and safety of Iruplinalkib in the treatment of ALK-positive NSCLC in China. The study aims to enroll ALK-positive NSCLC patients who have undergone treatment with Iruplinalkib prior to enrollment. Demographic information, medical history, Iruplinalkib-containing treatment regimens, …

18 years of age All Phase N/A

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