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Found 1,623 clinical trials
Z Zeynep Hazar, Prof. Dr.

Whole Body Vibration Therapy in Individuals With Type 2 Diabetes

The aim of this interventional study is to investigate the effect of whole body vibration therapy on muscle oxygenation, vibration sensation, functional capacity and balance in individuals with Type 2 diabetes. The main questions aimed to be answered are: Does whole body vibration therapy affect peripheral muscle oxygenation? Does whole …

18 years of age All Phase N/A
J Jianping Liu

The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes

To evaluate the effects of subcutaneous injection of semaglutide for 12 weeks on patients with type 2 diabetes mellitus (T2DM), compared with concurrent energy-restricted management, on glycemic control, weight loss, inflammatory markers, liver fat content, and other parameters. The study also observed the subcutaneous and visceral fat of the participants …

18 - 75 years of age All Phase 4
N Nuong Truong, MD

RCT Glargine vs NPH for Treatment of DM in Pregnancy

We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy. Currently, many hospitals differ among use of insulin for management of DM in pregnancy, with NPH, glargine and detemir being …

18 years of age Female Phase 3
U Umar Wahab

Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study

Study Objective To evaluate the safety and tolerability of Empagliflozin with or without metformin in patients with Type II Diabetes Mellitus in the Pakistani population. Study design Open-label, prospective, observational, single arm, multi-center, post-marketing surveillance study. Sample size The estimated sample size will be n=156. Duration of study 12 months …

18 - 65 years of age All Phase 4

Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes

The aim of this study is to determine if suvorexant can help treat the severity of insomnia in midlife women who are pre-diabetic.

40 - 65 years of age Female Phase 4
S Suzy Laroche

Surgery Versus Best Medical Management for the Long Term Remission of Type 2 Diabetes and Related Diseases (REMISSION)

Bariatric surgery procedures induce weight loss through restriction and/or malabsorption. The mechanisms underlying type 2 diabetes remission and others metabolic improvements after Roux-en-Y Gastric Bypass (RYGB), sleeve gastrectomy (SG) or biliopancreatic diversion with duodenal switch (BPD-DS) have not yet been formally studied. The investigators propose a longitudinal study with the …

18 - 60 years of age All Phase N/A
A Andrea Alioto, PhD

Dementia and Diabetes Prevention Program

This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in …

60 years of age All Phase N/A
Y Yuyin Chen

Clinical Study of the Use of Amino Acid Peritoneal Dialysate in Diabetic Patients

The study is a single center, open, prospective, self controlled clinical study. The patients with diabetes who are to be enrolled in peritoneal dialysis are to observe the changes of glycosylated hemoglobin relative to the baseline 90 days after using amino acid (15) peritoneal dialysis solution.

18 - 75 years of age All Phase N/A
S Sara K Rosenkranz, PhD

Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County

This pilot and feasibility study aims to assess the effectiveness of a nutrition education intervention using the Cooking Matters for Adults Curriculum (SNAP-Ed). The study compares this standard curriculum with an enhanced version that includes the same curriculum but has additional components, incorporating specific information related to type 2 diabetes. …

18 years of age All Phase N/A

Non-surgical Periodontal Therapy and Kidney Outcomes in Type 2 Diabetes Mellitus

Brief Summary (Lay Description) This research study is being conducted to understand whether treating gum disease (periodontitis) can help improve kidney health in patients who have type-2 diabetes mellitus (T2DM). Both diabetes and gum disease are common long-term conditions that often occur together. People with uncontrolled diabetes are at risk …

30 - 65 years of age All Phase N/A

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