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Found 65,447 clinical trials
K Karen Thompson, MA

Health Literacy in Geriatric Patients

Health Literacy is one's ability to understand health information well enough to make informed decisions about their health. Limited health literacy makes it hard for people to understand complex health issues and follow health care recommendations. Limited health literacy is associated with adverse health outcomes such as higher mortality, increased …

65 - 110 years of age All Phase N/A
O Osvaldo Fariña

Regional Assessment of the Risk of Lung Injury in Ventilated Patients

Specific characteristics of the lung, such as its functional capacity, heterogeneity, and recruitment potential, can influence the development of ventilator-induced lung injury even under safe ventilation conditions. Objective: To evaluate the risk of ventilator-induced lung injury at the regional level in patients with acute respiratory distress syndrome ventilated with similar …

18 - 75 years of age All Phase N/A
S Stefano Zaffagnini, MD

Evaluation of Clinical and Radiographic Outcomes of Surgically Treated Multiligamentous Knee Injuries

Multiligament knee injuries are typically caused by high-energy mechanisms and are classified according to the number of ligaments involved using Schenk's classification (Knee Dislocation) into KD 1, KD 2, KD 3, and KD 4. These types of injuries can have devastating consequences on the individual's quality of life, affecting their …

18 - 65 years of age All Phase N/A

Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients

Rationale: While total knee replacements (TKA) are one of the most commonly performed surgical procedures in the United States, this procedure can also be very painful. Postoperative mobilization and rehabilitation is vital to a patient's recovery, but inadequate pain control can impede patients' progress. Diaphragmatic breathing is an additional non-pharmacological …

50 - 90 years of age All Phase N/A
R Rodney A Gabriel, MD

Leveraging Artificial Intelligence and Multi-Omics Data to Predict Opioid Addiction

The primary goal of this proposal is to validate a novel genomic and microbiome predictive model that may be used to assess a person's risk of developing opioid use disorder (OUD). The following will be tested: (1) MODUS (Measuring risk for Opioid use Disorder Using SNPs), which is a genomic …

18 years of age All Phase N/A
G Giovanni Battista Forleo, Dott.

The Predictive Value of Dobutamine Echo-stress in the Clinical Response to CCM Therapy in Advanced HF

The goal of this observational cohort study, which is both retrospective and prospective, is to evaluate the long-term clinical and instrumental response to Cardiac Contractility Modulation (CCM) treatment in adult subjects suffering from symptomatic heart failure (HF) due to systolic left ventricular dysfunction, despite adequate medical therapy. Based on the …

18 years of age All Phase N/A

Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess the change in disease activity of risankizumab treatment in adult participants with moderate to severe UC in real-world clinical practice. Risankizumab …

18 years of age All Phase N/A
H Hieba gamal Ezzelregal

Association Between Plasma D Dimer in Adult CAP and Severity of Inflammatory Response and Survival

This is an observational study aiming to investigate the association between elevated plasma D-dimer levels and the inflammatory response, as well as the impact on survival in adult patients with community acquired pneumonia. the study participants will be subjected to sampling for D dimer and calculation of CURB 65 score. …

18 years of age All Phase N/A
B Bruno Pereira, Principal Investigator

Evaluation of the Safety and Performance of the Neocement® Inject P

This study aims to collect real-world clinical data to gather information on the performance and safety of the Neocement® Inject P when used according to its intended purpose and current clinical applications. The results of the clinical study will serve as clinical evidence for the device's clinical evaluation, targeting submission …

18 years of age All Phase N/A
d dilan demirtas karaoba, asst. prof

Evaluation of Joint Position Sense in Healthy Individuals

It was aimed to measure the elbow joint position sense in healthy individuals in the case of a closed kinetic chain and to compare it with the measurement made in the case of an open kinetic chain.

18 - 25 years of age All Phase N/A

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