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Found 65,447 clinical trials
L Laura Ruebush, PhD

Metabolic and Functional Consequences of Aging in Health and Disease

Considerable heterogeneity in the aging population has been observed. The exceptional longevity of individuals reaching 100 years old, so-called centenarians may be an example of life-long healthy aging, or added years may be spent in poor health with decreased physical and cognitive functioning. Current knowledge of the aging experience and …

50 years of age All Phase N/A
A Angela Maria Valsecchi, MD

Study About Hepatic Toxins Kinetic and Evaluation of Organ Damage in Acute on Chronic Liver Failure (ACLF) Patients

Spontaneous Observational Prospective Multicenter study of all patients admitted to Intensive Care with a diagnosis of Acute on Chronic Liver Failure (ACLF) of grade ≥ 2 for which the use of the system will be authorized extracorporeal purification with DM CYTOSORB. The hypothesis underlying the study is to evaluate whether …

18 years of age All Phase N/A
C Conor McNamee, MB BCh BAO

SYMPHONY™ OCT System for Instabilities of the Upper Thoracic and Cervical Spine

This will be a prospective, multi-centre study at a National Tertiary Referral Centre for spinal trauma and spinal cord injuries, serving a catchment area of 5 million people. Consecutive patients undergoing posterior-only surgery or combined anterior and posterior surgery for degenerative cervical pathology, traumatic spinal fractures or dislocations, failed previous …

18 years of age All Phase N/A
A Alexandra Dupire

Decompression of Pudendal and Inferior Cluneal Nerves Using Robot-assisted Laparoscopy for Entrapment Neuralgias : the X-DECO Study

The objective of our study is to evaluate the efficacy of the laparoscopic robot-assited approach after 1 year of follow-up, on pain experience, and anxiety, depression, post-traumatic stress syndrome and quality of life.

18 years of age All Phase N/A
S Stefano Zaffagnini, MD

Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial Sensors

evaluate the clinical outcome of the implantation of a specific primary TKA model implanted with the aid of inertial sensors for the execution of bone cuts through the administration of questionnaires for the calculation of clinical-functional scores;

50 - 85 years of age All Phase N/A
Y Yi Zhou

Analysis of Various Treatment Methods of Granulomatous Lobular Mastitis

Granulomatous lobular mastitis (GLM) is a rare benign breast disease that is difficult to distinguish from breast cancer based on clinical and imaging findings, and there is currently no standard treatment. This study aims to analyze the clinical characteristics and demographic data of GLM patients and to compare the overall …

15 - 65 years of age Female Phase N/A
G Giulia Basile, MPharm

Early Retinal Neurodegeneration As Risk Factor, Biomarker and Pharmacological Target of Diabetic Retinopathy

Despite the evidence that diabetic retinopathy (DR) remains the first cause of blindness among the working-age population, it lacks a specific preventive treatment. This is because early mechanisms leading to the development of DR have been, until recently, unknown. Recent studies have suggested that the early stages of DR could …

40 - 80 years of age All Phase N/A
M Matthew VerMilyea, PhD

The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF

The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.

years of age All Phase N/A

Assessing the Effect of Different Grades of Chondromalacia on Static and Dynamic Balance Using Biodex Balance System

The aim of this study is to investigate the effect of grades of chondromalacia on static and dynamic balance.

18 - 40 years of age All Phase N/A

Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards

The goal of this observational study is to learn about the disability profile during transition from ICU to hospital wards of delirium patients, including cognitive impairment, physical dysfunction and psychological disorders. The main question it aims to answer is: What is the main rehabilitation problem during transition from ICU to …

18 - 100 years of age All Phase N/A

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