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Found 64,783 clinical trials
M Matthias D Zink

Non-invasive Differentiation of Supraventricular Tachyarrhythmia

Questionnaire for supraventricular tachycardia: About history and targeted diagnosis of supraventricular tachycardia Extended Signal-averaged ECG for detailed P-Wave analysis and to calculate a virtual atrial electrocardiogram (ECG)

18 years of age All Phase N/A

The French EsoGastricTumours Data Base

This retrospective study aims at evaluating the outcomes of gastrointestinal stromal tumor after surgery.

18 - 90 years of age All Phase N/A
A Aleksey Kurguzov

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

Polymorphism in the GUCY1A3 gene worsens the activity of rCC, causing vasoconstriction and increased platelet aggregation. Studies have shown the association of the GUCY1A3 gene with the risk of coronary heart disease and its complications, with ischemic stroke

18 - 90 years of age All Phase N/A

Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study

The primary objective of the study is to create a biobank of oral smears permitting to identify the genetic locus/loci associated with an increased risk to develop meningiomas after cyproterone acetate (CPA) (Androcur®) treatment, using a GWAS approach. As the secondary objectives, the study aims: to evaluate the importance of …

18 years of age Female Phase N/A
C Charles Muller, PhD

SpermQT Prospective Observational Trial

The goal of the study is to validate the ability of the Epigenetic Sperm Quality Test (SpermQT) to assess a man's sperm quality and corresponding success of infertility treatments.

18 - 45 years of age All Phase N/A
V Valeria Stella Vanni

Looking for a Blood Epigenetic Signature to Predict Female Infertility

The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality. Specifically, our project aims to build an epigenetic clock for MGCs by using outcomes that are certainly related to female fertility. The validation of such findings will …

18 - 43 years of age Female Phase N/A
P Peter Ka-Fung CHIU, FRCS, PhD

Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection

This is a prospective clinical study recruiting 510 men at risk of PCa to undergo urine, blood, AI-assisted ultrasound and AI-assisted MRI investigations to stratify risk of clinically significant PCa (csPCa). (sample size calculation in section 5)

18 years of age Male Phase N/A
G GMALL Study Center

GMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and Outcome of Adult Acute Lymphoblastic Leukemia (ALL) Patients and Related Diseases Associated With a Prospective Collection of Biomaterial

The GMALL registry serves the purpose of ALL research and quality assurance. The Registry collects data about diagnostics, treatment and outcome of Adult ALL Patients in the clinical routine, whether or not the patient is treated within a clinical trial.

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

This study will investigate how, why and under what conditions eosinophils (a type of white blood cell) become activated and will examine their function in immune reactions. Eosinophil counts often rise in response to allergies, asthma, and parasitic worm infections. They can also go up in uncommon autoimmune conditions and, …

1 - 100 years of age All Phase N/A

Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 Questionnaire

Adolescent Idiopathic Scoliosis (AIS) is an unexpected curvature of spine at teenage. AIS causes mainly unpleasant appearance, and sometime comes with pain and difficult to locate or move around. When the spinal curve, or "Cobb angle", increases with time, the investigators call it severe condition when the Cobb angle is …

years of age All Phase N/A

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