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Found 64,783 clinical trials

Circulating Markers for Ischemic Heart Disease

The purpose of this research is to determine if two proteins in the blood are increased during acute myocardial infarction and whether their levels are higher in those who develop heart failure than those who do not. These two proteins are produced and potentially released when the heart muscle is …

18 years of age All Phase N/A
M Megan Tones, PhD

The Global Angelman Syndrome Registry

The Global Angelman Syndrome Registry is an online patient organisation driven registry to collect information about the natural history of children and adults with Angelman Syndrome. The registry will facilitate 1) recruitment for clinical trials into therapies and interventions to benefit participants with Angelman Syndrome and their families, and 2) …

years of age All Phase N/A
L Luca Pagliardini

Oxidative Stress and Male Infertility.

Study Aims: To evaluate the impact of oxidative and nitrosative stress, as well as DNA methylation, on male reproductive health. This is achieved by analyzing urinary biomarkers: 8-oxoGua, 8-oxoGuo, 8-oxodGuo, 3-nitrotyrosine (3-NO2Tyr), 5-methylcytidine (5-MeCyt), and cotinine in infertile and fertile males. Study Design: A prospective observational case-control study comparing infertile …

18 - 50 years of age Male Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Brain Stimulation and Vision Testing

Background -The brain has two systems for recognizing objects. One system recognizes what an object is, and the other system recognizes where the object is located. However, there is much about how the brain handles and interprets the information from these two systems that is still unclear. Researchers want to …

18 - 50 years of age All Phase N/A
W Wenhao Zhou, Doctor

Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units

The purpose of study is to evaluate the benefits of using the Next Generation Sequencing Technology to diagnose birth defects and genetic diseases. The results from genomic sequencing can also significantly shorten the time of examination, improve the diagnosis rate, guide the clinical treatments. So the ultimate goal is individualized …

- 28 years of age All Phase N/A

Real World Evidence Clinical Utility Study of KidneyIntelX

The purpose of this study is to assess the impact of the KidneyIntelX assay utilized as part of the current standard of care on the management of patients seen in the primary care physician's office at Mount Sinai.

23 years of age All Phase N/A

Instrumented POsterolateral Arthrodesis for Adolescent Idiopathic Scoliosis

The study population concerns adolescent patients with idiopathic scoliosis which requires surgical management and who have a longer waiting period of 6 months. The aim of this study is to research the predictive factors of an improvement in the quality of life of adolescents who have had surgery.

12 - 20 years of age All Phase N/A

Prognosis of Coronary Stenosis Based on Intracoronary Imaging; A Multicenter, Prospective Observational Study

The purpose of this study is to evaluate the prognosis of coronary stenosis based on intracoronary Imaging.

19 years of age All Phase N/A
Y Yannick BEJOT

Medical-economic Evaluation Comparing Intensive Outpatient Monitoring of Neuro-cardiovascular Diseases by Nurses, Doctors and Hospital and Private-sector Pharmacists, Compared to Usual Monitoring.

Cerebral Vascular Accidents (stroke) and Myocardial Infarction (MI), which share the same risk factors, treatments and pathophysiological mechanisms, have become two major public health problems due to the increase in their prevalence rate and the longer survival after such an event in developed countries. International data, including French data and …

18 years of age All Phase N/A
D Duk-woo Park, MD

Transpacific TAVR Registry

This registry evaluates the long-term outcome of Transcatheter aortic valve replacement (TAVR) in real-world clinical practice.

19 years of age All Phase N/A

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