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Found 64,783 clinical trials

A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH

The primary aim is to establish a prospective cohort of patients with plasma cell disorders (PCDs). All of the hospitalized PCD patients who are willing to sign the informed consent form (ICF) will be included in this study. Clinical characteristics, treatment options and responses will be collected. Peripheral blood, bone …

years of age All Phase N/A
L Lijuan Bu, PhD

Multi-center Study on New Cardiovascular Remodeling and Function Parameters in Hypertension

The investigators want to explore the relationship between different configurations of hypertension and the incidence of cardiovascular events by the guidelines reference range and EMINCA recommended reference range. Then the investigators want to enroll twenty research centers and 2200 hypertensions were planned to be collected and followed up in the …

30 - 75 years of age All Phase N/A
B Benoît Lamarche, PhD

NutriQuébec: a Web-based Prospective Cohort Study to Monitor the Population's Eating Habits in the Province of Québec.

The epidemic of non-communicable diseases such as cardiovascular diseases and type 2 diabetes is attributable in large part to unhealthy eating habits and physical inactivity. In the Fall of 2016, the Québec Government launched its first-ever Government Health Prevention Policy (PGPS) to act on a set of factors to improve …

18 years of age All Phase N/A
B Brion Beerle, MD

The Alaska Oculocardiac Reflex Study

Observation study monitoring vital signs and anesthetic variables particularly heart rate during prospective, ocular manipulation and specifically uniform tension on extra ocular muscles during strabismus surgery. IRB approval from 1992 covered in letter from then IRB chair Dr. Judith Whitcomb, Anchorage, Alaska (letter 10/2020).

1 - 100 years of age All Phase N/A

Developement and Validation of the Health Behavior Questionnaire Towards Deprescribing (HBQtD)

The goal of this observational study is to: develop and validate a health behavior theory-based questionnaire to examine the older adults' and informal caregivers' determinants of deprescribing behavior assess the psychometric properties of this new instrument analyze the moderating influence of health literacy and locus of control on the effect …

18 years of age All Phase N/A
E Eva Schäffer, Dr.

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

The PASS-PD study is set out to screen individuals from the general population with an increased risk for the development of Parkinson's Disease (PD) and to investigate this highly enriched cohort longitudinally for five year. A special focus is placed on implementation of ethical standards for early risk disclosure in …

50 - 99 years of age All Phase N/A
M Matthew Krebs, Prof

Tumour Characterisation to Guide Experimental Targeted Therapy - National

The primary aim of TARGET National is to establish a national framework to offer molecular profiling of circulating tumour DNA and/or tumour tissue (optional) to patients with advanced solid cancers referred to any of the Experimental Cancer Medicine Centres (ECMCs) across the UK, in order to help decision making for …

16 years of age All Phase N/A
J Julie A. Ward, BSN

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life

To assess short and long term outcomes after minimally invasive esophagectomy compared to open esophagectomy. To compare both standard outcome measures as well as patient derived outcome measures, in particular, quality of life (QOL). To look at the applicability of this QOL instrument to this patient group.

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Adaptive Optics Retinal Imaging

Background By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing the retina. One way called adaptive optics may help detect problems earlier. Objectives To study if adaptive optics can help find better ways to diagnose, …

12 - 120 years of age All Phase N/A

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

The purpose of this prospective observational study is to collect data from participants who have recently had an allogenic Stem Cell Transplant(alloSCT) and are at risk of Chronic Graft Versus Host Disease(cGVHD)

18 years of age All Phase N/A

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