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Found 65,447 clinical trials
S Sharon Svoboda, RN

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

The purpose of this study is to see how much pain intensity is affected by high frequency spinal cord stimulation therapy in individuals with serious brachial plexus injury.

18 years of age All Phase N/A
I Irene MJ Mathijssen, MD, PhD, MBA-H

Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs

RESEARCH QUESTION Is the effectiveness of conservative policy comparable to that of surgery in children with trigonocephaly, with regard to clinical outcomes and psychosocial functioning, stress for parents, and costs? DESIGN Observational cohort study in children, aged 0 to 8 years old, with trigonocephaly, excluding metopic ridging (physiologic early closure …

- 8 years of age All Phase N/A

Reducing Patient Memory Recall in the Burning Mouth Patient Population

The goal of this study is to learn about burning mouth syndrome symptoms in real time in patients with burning mouth syndrome. The main questions it aims to answer are: (1) To test the ability of a smartphone app to collect repeated observations of individual data to assess fluctuations in …

18 years of age All Phase N/A

Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

The overall objective of this study is to develop a novel couple-based mindfulness intervention aimed at reducing distress in patients with metastatic colorectal cancer (mCRC) and their partners.

18 - 85 years of age All Phase N/A

Long-term Observational Study to Evaluation the Safety of FURESTEM-RA Inj(K0202)

Long-term Observational Study to Evaluation the Safety of FURESTEM-RA Inj(K0202)

19 - 80 years of age All Phase N/A

PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

Background Sometimes people with HIV, the virus that causes AIDS, can have new or worsening symptoms soon after starting HIV medications. Often these symptoms are caused by immune reconstitution inflammatory syndrome (IRIS). Researchers want to study why and how people develop IRIS and how best to prevent and treat it. …

18 - 100 years of age All Phase N/A
J Jennifer Moorer

Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR)

Results from large clinical trials demonstrate a strong association between lipid abnormalities and progression of the most common microvascular complication, diabetic retinopathy (DR). We found that activation of a master regulator of cholesterol metabolism, the nuclear hormone receptors liver X receptors (LXRα/LXRβ), prevents DR in rodent models. In this application, …

21 - 98 years of age All Phase N/A
J Jan Vagedes, MD, Dr

Antibiotic Prescription in Children Hospitalized for Community-acquired Pneumonia

A study to observe how often antibiotics are prescribed in children hospitalized for pneumonia and how doctors decide if a child needs antibiotics or not. Parent satisfaction will also be recorded.

3 - 18 years of age All Phase N/A
M Markus M Heiss, Prof Dr

VAC-Stent Registry

This registry is intended to collect data on quality assurance and use of the VAC-Stent® and thus verify the suitability of the VAC-Stent® for sealing leakages in the oesophagus or colon. Furthermore, the safety and efficacy of the VAC-Stent® shall be proven.

18 years of age All Phase N/A
A Amy Vierhile, RN PNP

Clinical and Neuropsychological Investigations in Batten Disease

This study aims to assess the natural history of Batten disease (Neuronal Ceroid Lipofuscinosis) by obtaining information about the motor, behavioral, and functional capabilities of individuals with Batten disease. This study will also refine and validate the Unified Batten Disease Rating Scale (UBDRS) as a clinical rating instrument for Batten …

years of age All Phase N/A

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