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Found 64,778 clinical trials
N Nicolas Gninenko, PhD

Tinnitus Patient Preferences Survey

The goal of this survey is to assess several aspects related to patient preferences regarding interventions for alleviating tinnitus through invasive electrical brain stimulation (neuromodulation). This survey covers the acceptance of a surgically-placed brain implant, of its associated risks related to the neurosurgical procedure, usability considerations, and the willingness/ability to …

18 years of age All Phase N/A
G Giuseppe Petralia, MD

Response Evaluation of Cancer Therapeutics in Metastatic Castration-Resistant Prostate Cancer to the Bone

This study is aimed to compare whole body MRI (WB-MRI) with Bone Scintigraphy (BS) and Computerized Tomography (CT) scans in patients receiving treatment for metastatic castration-resistant prostate cancer to the bone. This is a monocentric, prospective observational study.

18 years of age Male Phase N/A
K Kubra Kardes

Emotional Suppression in Elderly Individuals

The world's population is aging, and the proportion of individuals aged 60 and over is rapidly increasing. With aging, the prevalence of both physical and psychological health problems increases, negatively impacting quality of life. Chronic musculoskeletal pain, one of the most common health problems among older individuals, limits their daily …

65 years of age All Phase N/A
J John R Speakman, PhD

The Associations Between Gut Length, Gut Microbiota and Food Assimilation

The purpose of this observational study is to explore the relationships between gut length, the microbiota and food energy assimilation rates in humans.

18 - 40 years of age All Phase N/A
A Andreas Kappel, Ass. Prof

Wearable Sensors for Monitoring Recovery After Total Knee Arthroplasty

The goal of this observational study is to investigate the potential of wearable sensors for monitoring the postoperative recovery of patients after TKA. The main question the study aims to answer is: • whether alterations in gait characteristics and the changes in PA levels measured by wearable PA trackers can …

18 years of age All Phase N/A
M Monserrat SIERRA COLOMINAT

Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.

Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact. This score was initially evaluated and validated on an adult population. ) In …

1 - 18 years of age All Phase N/A
F François Sévrin, MD

Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

This non-interventional study aims to develop spatial proteomics for analyzing small FFPE tumor samples in rhabdomyosarcoma. It will identify molecular signatures linked to tumor regions, subtypes, survival, and treatment resistance, using pre-existing samples and data.

- 25 years of age All Phase N/A
A Andrey Belkin, MD

Evaluation of the Efficacy of Permanent Course Combined Therapy With CYTOFLAVIN® Intravenous Solution and CYTOFLAVIN Tablets, at 2-3 Stages of Rehabilitation of Patients With Post Intensive Care Syndrome

Post intensive care syndrome (PIC syndrome) is an important problem in modern intensive care strategy. Understanding the mechanisms of PIC syndrome helps prevent it in patients with respiratory, neuromuscular transmission, and cognitive impairments that require prolonged support of vital functions. Significant role in the formation and severity of PIC syndrome …

18 years of age All Phase N/A

The Biomechanical Outcomes of Autologous Chondrocyte Implantation

Injury to the knee can damage the lining of the knee's bones, called cartilage. Cartilage injuries cause pain and limit movement, making activities like walking, playing sports, and working difficult. Cartilage cannot repair itself well, so surgery is often needed to repair it. People who have cartilage repair surgery want …

18 years of age All Phase N/A

This Study Aims to Measure the Effect of Acute Hospitalisation on the Physical and Cognitive Functioning of Older Orthopaedic Patients (Aged 65 or Above).

This study aims to investigate the impact of hospitalisation on physical and cognitive performance in patients aged 65 and older admitted with an orthopaedic injury. This will be achieved by asking patients to participate in a series of physical and cognitive performance questionnaires and tests. These questionnaires and tests will …

65 years of age All Phase N/A

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