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Found 65,447 clinical trials

A Study of YL201 in Combination With Toripalimab and With or Without Cisplatin in Nasopharyngeal Carcinoma.

This is a multicenter, open-label, Phase Ib/II study conducted in China to evaluate the safety, efficacy, and pharmacokinetic (PK) characteristics of YL201 combined with Toripalimab (doublet regimen) or YL201 combined with Toripalimab and Cisplatin (triplet regimen) in subjects with recurrent or metastatic nasopharyngeal carcinoma.

18 - 75 years of age All Phase 1/2
M Mohammed S ElSharkawy, MD

Analgesic Efficacy of Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

This study aims to compare the analgesic efficacy of multiple mid-transverse process to pleura (MTP) block and PCA in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.

18 years of age All Phase N/A
J Jianjun Yang, MD

A Phase Ⅱ/Ⅲ Study of HRS-2129 for Postsurgical Pain Management in Abdominal Surgery

This is a phase II/III, multi-center, randomized, double-blind, comparator-controlled study to evaluate the efficacy and safety of HRS-2129 for postoperative pain management in abdominal surgery.

18 years of age All Phase 2/3
T Theis Itenov, MD, PhD

Feasibility Performance Study of ABL90 FLEX PLUS HEM

This feasibility performance study evaluates the ABL90 FLEX PLUS HEM device for its analytical performance in a clinical setting. The study aims to evaluate the performance of the hemolysis detection feature.

18 years of age All Phase N/A
J Jean-Phillipe LANOIX, Dr

Early Discontinuation of Antibiotic Therapy in Elderly Patients Hospitalized for a Viral Infection

Among winter respiratory viruses, influenza is the most common and therefore responsible for the highest mortality, but parainfluenza and RSV viruses have an even higher risk of mortality (1.6 to 1.9 times), this toll being paid mainly by the elderly and co-morbid population. Futhermore, SARS-Cov2 will probably become endemic and/or …

65 years of age All Phase N/A
S Site Contact

Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation

Dravet syndrome with SCN1A gene mutation is a developmental and epileptic encephalopathy characterized by treatment-resistant epilepsy and global developmental delay. Despite the considerable attention recently Dravet syndrome (DS) in drug development, studies characterising the progression of the neurodevelopmental phenotype over time remain limited. In particular, many previous studies of natural …

6 - 21 years of age All Phase N/A
D David C Shepherd, PhD

R61/33 - VR Study Phase 4

The goal of this larger parallel group randomized trial is to test the impact of a virtual reality program for improving the ability of emerging adults (age 18-25) with attention deficit hyperactivity disorder (ADHD) to stay focused while completing homework and studying. This study compares the impact of using a …

18 - 25 years of age All Phase 4
C Catherine Sadler

Online Brief Advice Intervention for Heavy Cannabis Users

This project will evaluate whether a brief online intervention focused on cannabis withdrawal can increase awareness and insight about cannabis use disorder among daily cannabis users. The study will employ a randomised controlled trial design comparing an intervention consisting of a short educational video on cannabis withdrawal and personalised feedback …

18 years of age All Phase N/A
F Fuming Qiu, PhD

A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors

This study is a single-arm, open-label, dose-escalating + dose-expansion clinical study, aiming to evaluate the safety and efficacy of CEA-targeted CAR-T cell preparations, and to preliminarily observe the study drug in CEA-positive advanced malignant tumors. The pharmacokinetic characteristics of CAR-T cell preparations for the treatment of patients with CEA-positive advanced …

18 years of age All Phase 1

Safety and Effectiveness of Sculptra 011611 for Improvement in Appearance of Gluteal Skin Irregularities

The main purpose of the study is to investigate the safety and effectiveness of Sculptra 011611 for improvement in appearance of gluteal skin irregularities.

18 years of age Female Phase N/A

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