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Found 64,778 clinical trials

Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients

PRO-RED is a prospective, longitudinal, and multicenter observational study. Enrolled patients will be followed for 6 months in at least monthly intervals in terms of their received red blood cell transfusions and routine myelodysplastic neoplasms (MDS)-associated clinical parameters. In addition, the participating subjects will be provided with a digital/mobile application …

18 years of age All Phase N/A
M Mette MM Jensen, MD

Inuit and Cold Exposure

Brown adipose tissue (BAT) produces heat through non-shivering thermogenesis. It is activated by cold exposure, and when activated it utilizes fatty acids and glucose in order to produce heat. The tissue is especially present in newborns, who not yet have gained a layer of insulating fat to protect from heat …

18 - 50 years of age All Phase N/A
S Suki Liyanarachi

Gastrocnemius Tightness and Foot Pain in Children

Foot and leg pain among otherwise healthy children is a common reason for referral to our pediatric orthopaedics outpatient clinic. The pain is often intermittent and transient, but for some the pain is more dominating and has an impact on the child and families. Children grown and have normal anatomical …

4 - 16 years of age All Phase N/A
J Jennifer H Kuo, MD MS

RFA Treatment for Papillary Thyroid Microcarcinoma

Thyroid surgery has always been the mainstay of treatment for thyroid cancer. Thyroid surgery carries a low risk of complications that include recurrent or superior laryngeal nerve injury leading to voice changes, hypoparathyroidism, hypothyroidism with need for thyroid hormone supplementation, and unsightly scarring. Although many patients with thyroid cancer find …

18 years of age All Phase N/A
A Arvid Rongve, Phd

ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB)

The goal of the study is to develop predictive algorithms and digital biomarkers to capture disease fluctuations in (prodromal) dementia with lewybodies (DLB) patients and to improve treatment, diagnosis and prognosis of the study drug Ambroxol, used in the ANeED study. This project is an additional study to the ANeED …

50 - 85 years of age All Phase N/A
M Michael Young, MD

An Ethical Approach to Detecting Covert Consciousness

This study aims to develop an ethical approach to developing and deploying novel neurotechnologies to aid in the detection of consciousness and prediction of recovery after brain injury.

18 years of age All Phase N/A
K Kimberly M Baynes, COA

Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant

We will prospectively observe patients with uveitis who are either active or were recently active in the previous 6 months and are treated with the i-FA implant. All of the patients will have standard clinical exams at baseline and image quantification of their inflammation using OCT, OCTA and UWFFA (if …

18 years of age All Phase N/A
A Antonio Liguori, MD

Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients

A lot of different early and late complications may occur after liver transplantation. They could be related to surgical procedure, to infectious diseases or immuno-mediated diseases (acute cellular rejection, ACR). Almost all of those complications are characterized by an elevation in liver enzymes (ALT, AST and GGT) and a decline …

18 - 75 years of age All Phase N/A
M Matthew Koff, PhD

Using MRI To Detect Soft Tissue Reactions And Implant Integration As Related To Implant Modularity

Patients with a total hip replacement may require early revision surgery due to an adverse local tissue reaction or bone resorption that occurs due to wear debris released from the implant. MRI provides a non-invasive biomarker for clinicians and surgeons to detect early adverse synovial reactions which may exist in …

21 - 95 years of age All Phase N/A
X Xiaoying Zhu, OD, PhD, MD, MS, FAAO

Assessing Dynamic Reading Behaviors Using Eye-Tracking Tobii Glasses

HYPOTHESIS Horizontal convergence tracked with Tobii glasses is a reliable substitute for accommodation in young myopes and hyperopes with normal accommodative amplitudes Young mypopes and hyperopes demonstrate different reading behaviors during near work AIMS & OBJECTIVES: Compare the accommodative responses measured with the Grand Seiko open-field autorefractor to those derived …

18 - 30 years of age All Phase N/A

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