Found 64,778 clinical trials
Long-term Follow-up in Patients Included in the European Sleep Apnea Data Base (ESADA)
The European database ESADA, containing data from more than 30,000 patients with very different severities of obstructive sleep apnea (OSA) syndrome, prospectively collects data from patients referred to academic sleep laboratories in many European countries (https://esada.med.gu.se/). Since 2007, Grenoble is one of the two French centers with Paris and is …
Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia. Heart failure patients with and without sarcopenia will be scanned using MR Fingerprinting and an existing Post-exercise phosphocreatine (PCr) recovery …
Assessing the Precision of Convolutional Neural Networks for Dental Age Estimation From Panoramic Radiographs
The aim of this study is to assess the accuracy of a convolutional neural network in dental age estimation from digital panoramic radiographs. The reference standard will be the chronological age of the patient.
ePRO for the Timely Detection of Side Effects in Cancer Patients Undergoing CAR T Immunotherapy
This study is designed as a feasibility study implementing electronic Patient Reported Outcomes (ePRO) in CAR T treatment for hematological malignancies, in order to describe AE reporting. ePRO assessments will be explored for their feasibility to engage in monitoring and management of CAR T-related toxicities as well as using these …
Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, primarily affecting overweight females of childbearing age. Typically, patients experience headache and visual symptoms due to increased intracranial pressure (ICP) and papilledema. The diagnosis is difficult, and outcomes vary from no sequelae to blindness or chronic headaches. No clear prognostic …
Isolation of Human Recombinant Therapeutic Monoclonal Anti-Pseudomonas Antibodies
Pseudomonas aeruginosa is a pathogenic bacteria for human, especially in hospital settings. It can sometimes be multi-resistant to many or even to all antibiotics usually used for its treatment. The aim of the study is to isolate and produce therapeutic antibodies against the bacteria Pseudomonas aeruginosa in order to provide …
MR Imaging Study of TBI in Children
This project will combine the data collected from structural and functional MRI scans and neuropsychology performance post-TBI in children. Patients will be followed for a year, in order to examine the brain and cognitive recovery post head injury.
Profile of Chronic Musculoskeletal Pain Patients Related to Treatment Adherence and Virtual Reality
Lack of adherence is one of the main problems of chronic musculoskeletal pain treatment. To improve adherence it is essential to take into account the characteristics of the patients and their thoughts and beliefs about pain. Virtual reality can present some advantages in the face of these problems too. The …
Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses
The investigators want to understand more about what kinds of health problems are caused by histiocytosis, what happens as a result of different treatments, and how ECD affects people's lives, their feelings and their attitudes. The investigators also want to learn how these things change over time for people with …
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.