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Found 64,783 clinical trials

Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD

Probiotics combined with enteral nutrition reduces postoperative infectious complications in PD

18 years of age All Phase 1/2
D Denzel LQ Drop, MD

ICU-VR Prior to ICU Admission

Rationale: A substantial proportion of the Intensive Care Unit (ICU) survivors develop psychological impairments due to their ICU admission. Several interventions to mitigate these impairments have been explored but lack a proper effect. Intensive Care Unit-specific Virtual Reality has proven to be potentially effective in treating PTSD and depression-related sequelae …

18 - 71 years of age All Phase N/A
C Coral Omene, MD,PhD

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast cancer. The study will also assess the safety and tolerability of tirzepatide, its feasibility based on discontinuation rates, and completion …

18 years of age All Phase 2
A Anna W Stenbro, Master's degree in Psychology,

Internet-based Versus Synchronous Cognitive Behavioural Therapy for Patients With Gambling Disorder

The aim of this two-armed, randomized controlled trial is to determine if internet-based cognitive behavioural therapy (CBT) is as effective as synchronous CBT (sCBT) for treating Gambling Disorder (GD) in adults. The main question it aims to answer is: Is the effect of the internet-based CBT ("SpilleFri") non-inferior to that …

18 years of age All Phase N/A
Y Yunfeng Xia, Dr.

The Effect of Active Exercise on Maintenance Haemodialysis Patients

The goal of this clinical trial is to discuss the effects of physical activity on nutrition, inflammation, muscle metabolism, and the occurrence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis. The main question it aims to answer is: can exercise improve nutritional and inflammatory status, enhance muscle strength, …

18 - 75 years of age All Phase N/A
N Nicole Stevens, PhD

Natural Product System and Lifestyle Modification

The goal of this clinical trial is to learn whether four dietary supplements and lifestyle changes can affect gene expression and blood markers in healthy volunteers. The main questions it aims to answer are: How does daily ingestion of dietary supplements affect gene expression and hsCRP and vitamin D levels …

30 - 55 years of age All Phase N/A
L Laura Ryan

Neonatal Mask Seal; a Two-handed Versus One-handed Approach: The NeoSeal Study

When babies can't breathe effectively, we can use a facemask to give them breaths and oxygen. The mask can be held with one or two hands, depending on the preference of the doctor. Both types of mask holds are recommended in international guidelines, but it is unclear which one is …

years of age All Phase N/A
K Kim Ross

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

To find the recommended dose of ulixertinib that can be given in combination with cetuximab and/or encorafenib to patients with unresectable/metastatic CRC and who have received EGFR or BRAF-directed therapy in the past.

18 years of age All Phase 1

Study of SC-102 in Patients With Advanced Solid Tumors

This study will evaluate the safety, PK profile, and anti-cancer efficacy of SC-102 in subjects with advanced solid tumors

18 - 75 years of age All Phase 1

Effect of Tubular Bandage Application on Peripheral Intravenous Catheter Usage Time and Infiltration in Children

In pediatric patients, placement of peripheral intravenous catheters is the most commonly performed invasive medical procedure. In addition to the administration of medications, parenteral nutrition, intravenous fluids, and blood products, peripheral intravenous catheters are placed prophylactically before procedures and for emergency use in unstable patients. One of the most common …

6 - 12 years of age All Phase N/A

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