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Found 64,778 clinical trials
D Denisa Muraru, MD, Ph.D.

In-depth Characterization of Atriogenic Secondary Tricuspid Regurgitation Due to Atrial Fibrillation

1050 patients with persistent/permanent atrial fibrillation (AF) will be studied using conventional and advanced (three-dimensional and deformation imaging) echocardiography. Patients with moderate/severe isolated secondary tricuspid regurgitation (STR) will undergo blood tests to assess their proteomic profile and cardiac CT to measure the tricuspid annulus geometry. The project will aim to …

18 years of age All Phase N/A

Production of Nonverbal Acoustic Signals and Resulting Physiological Responses

Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.Our studies aim to improve our …

18 - 80 years of age All Phase N/A
S Soo-Jeong Cho, MD, PhD

Intestinal Metaplasia Cohort for Gastric Cancer Prediction

In this study, we aim to establish a prospective cohort of patients with endoscopically and histologically confirmed intestinal metaplasia, collect gastric mucosal tissue samples from this cohort, and follow the development of gastric cancer over time.

18 years of age All Phase N/A

Total Joint Arthroplasty in a Pediatric Population

The primary purpose of this study is to examine the functional ability and quality of life in those patients who received a total joint arthroplasty (TJA) for reasons other than having a solid tumor at the location of the joint.

10 - 25 years of age All Phase N/A
S Semir Nouira, Professor

Management and Short Term Outcome of Traumatic Wounds in the Emergency Department

Identify the risk factors for complications as well as study the evolution of wounds sutured in the emergency room towards complications such as superinfections, necrosis, disunity of the stitches linked to inadequate initial care.

1 - 90 years of age All Phase N/A

SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access

SPECTA is a quality assured platform for collecting clinicopathologically annotated biological material, imaging data, operative images, environmental assessment, questionnaires as well as patient-reported outcomes from cancer patients to support biospecimen-based translational research and clinical cancer research, including biomarker discovery to improve the understanding of tumor biology and cancer patients care.

12 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Sample Collection From Healthy Volunteers for Assay Optimization

Background The Laboratory of Immune System Biology (LISB) works with other labs at the National Institutes of Health. They study how parts of living things come together to make a whole. LISB designs and improves research tests on human samples like blood and cells. In order to do its work, …

18 years of age All Phase N/A
D Dominique GENRE, MD

Institut Paoli Calmettes Chronic Lymphatic Leukemia Database

Database of Institut Paoli-Calmettes patients diagnosed with chronic lymphatic leukemia

18 - 95 years of age All Phase N/A
D Daniel Kreisel, MD, PhD

Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation

Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.

18 years of age All Phase N/A
M Markus Kneihsl, MD PhD

Reperfusion Injury After Endovascular Stroke Treatment

Endovascular stroke treatment with mechanical thrombectomy (MT) has become the standard therapy for intracranial large vessel occlusion (LVO). The most serious MT-related complication is secondary intracranial hemorrhage (ICH) occurring in 20-25%. Postrecanalization hyperperfusion might be an important risk factor/mechanism of MT-related ICH. In pilot studies, bedside transcranial Duplex sonography (TCD) …

18 years of age All Phase N/A

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