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Found 64,783 clinical trials

Coenzyme Q10 Role in Prevention of Contrast Induced Nephropathy in Acute Coronary Syndrome Patients.

In this study the investigators aim to study the effect of supplementation of CoQ10 in decreasing the incidence of contrast induced acute kidney injury in patients with acute coronary syndrome undergoing coronary angiography.

18 years of age All Phase 4

The UBC Long-distance Triathlon Adaptation Study

The purpose of this study is to investigate the effect of 12-months of individualized endurance-training (swimming, cycling and running) on physiological and psychological adaptations in exercise naïve individuals. Due to the potential seasonal changes that naturally occur in individuals across a year (even without training) the investigators will also compare …

19 - 39 years of age All Phase N/A
S Shukui Qin, M.D.

A Phase I Study of SIM0686 in Participants With Locally Advanced/Metastatic Solid Tumors

This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0686 in Adult Participants with Locally Advanced/Metastatic Solid Tumors

18 years of age All Phase 1
D Dominika M Pindus, PhD

Breaking Sitting with High-intensity Interval Training for Brain Health

This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in cognitively normal older adults. This trial will test the feasibility of HIIT breaks to sitting. It …

40 - 75 years of age All Phase N/A

Clinical Feasibility of the IMES Transradial Prosthesis

This study will evaluate the feasibility of using implanted myoelectric sensors (IMES) to control a transradial prosthesis

18 - 65 years of age All Phase N/A
A Abdullah Bennakhi, MD

A Pilot Study to Assess the Impact of Breath Awareness Using Pyramid on Symptoms of Anxiety and Depression in People with T2DM

Diabetes mellitus is rampant in the Middle East. It is a psychologically and behaviorally demanding disease; psychosocial factors are relevant to nearly all aspects of its management. Moreover, depression and diabetes are bidirectionally connected. Those with depression are at risk of developing diabetes and those with comorbid diabetes are at …

30 - 80 years of age All Phase N/A
P PARICHAY SINGHAL, PG STUDENT

Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal

To investigate The Effect of Sodium hypochlorite and Chlorhexidine as cavity Disinfectants on the post operative pain and Success of Partial Caries Removal in deep carious lesion with moderate pulpitis in permanent teeth

18 years of age All Phase N/A
P Philip Cheng, PhD

A Pilot of a Personalized Circadian MHealth to Improve Sleep in Night Shift Workers

The goal of this project is to establish the evidence base for equitable accessibility and implementation of the precision sleep medicine mobile application, SHIFT.

18 years of age All Phase N/A
Q Qiyong Zhu, MD

SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection

This is a Phase I/II gene therapy trial treating X-linked severe combined immunodeficiency (SCID-X1) using a self-inactivating lentiviral vector (ivlv-X1) to functionally correct the genetic defect. The primary objectives are to evaluate the safety and efficacy of the direct intravenous lentiviral gene transfer protocol.

1 - 1 years of age Male Phase 1/2

Pharmacokinetics and Safety of M107 Orally Disintegrating Tablet in Healthy Adults

Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of lobeglitazone administered as M107 Orally Disintegrating Tablet and Duvie tablet in healthy adult participants under fasted and fed conditions.

18 - 55 years of age All Phase 1

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