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Found 65,447 clinical trials
S Simon Wernhart, MD

Haemodynamics and Ventricular Arrhythmias During Exercise in Patients With Arrhythmogenic Cardiomyopathy

Patients with arrhythmogenic cardiomyopathy (ACM) are recommended to refrain from high intensity exercise due to an increased risk of malignant arrhythmias. However, little is known about the effects of prolonged, low-to moderate endurance or resistance exercise on the burden of arrhythmias or central haemodynamics. This pilot interventional study assesses the …

18 - 99 years of age All Phase N/A
D Dongyang Liu

A Clinical Study of GenSci134 in Healthy Male Adults

To check how safe and well-tolerated a single subcutaneous injection of GenSc134 is in healthy male volunteers

18 - 45 years of age All Phase 1
N Nicole Stevens, PhD

Metabolic and Epigenetic Impact of FAAH Inhibitors and OEA

The goal of this clinical trial is to learn whether a dietary supplement can affect gene expression and serum protein markers in healthy volunteers. The main questions it aims to answer are: Does the supplement affect gene expression and protein markers as measured in blood? How does daily ingestion of …

18 - 64 years of age All Phase N/A
H Huisheng Chen

Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With No Reperfusion Therapy (INSIST-NRT)

To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who missed recanalization operation.

18 years of age All Phase N/A
J Jeremy Ramdial, MD

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

To find a recommended dose of PRAME-TCR-NK cells that can be given to patients with AML or MDS.

18 - 80 years of age All Phase 1/2
R Richard B Woodbury, MPH

Jumpstarting Advance Care Planning With ANAI People

The older Alaska Native/American Indian (ANAI) population is increasing at twice the rate of the general population with a higher burden of serious illness. Older ANAI adults with serious illness are half as likely to have advance directives (AD), indicating a need for improved access to and utilization of advance …

40 years of age All Phase N/A
H Hongkun Cai

A Study of AL58805 in Patients With Advanced Tumors

This Phase I clinical trial is a dose-escalation, multicenter study in patients with advanced solid tumors. It includes tolerance studies of sequential multiple oral doses of AL58805 and pharmacokinetic studies of single and multiple doses, analyzing the tolerance range of multiple doses, observing the maximum tolerated dose (MTD) and dose-limiting …

18 years of age All Phase 1
M Mirjam Christ-Crain, Prof.

Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls

The investigator hypothesize that low-dose MDMA (3,4-methylenedioxymethamphetamine) will produce a sufficiently strong oxytocin stimulation in healthy controls and no relevant increase in patients. This study will confirm previously published data and provide important safety data with low-dose MDMA stimulation testing.

18 years of age All Phase N/A
A Amirul Faiz Luai, DDS, MSCDPH, PG Cert

Effectiveness of Metaverse-Based Immersive Technology Intervention for Oral Health Education: A Quasi-Experimental Study

To evaluate the effectiveness of pre- and post-intervention of oral health education using three interventions (conventional methods, mHealth, and the Metaverse platform) on the oral health status, knowledge, practices, and attitudes among secondary school students in Malaysia.

15 - 16 years of age All Phase N/A
H Havva Kaçan, Associete Proffesor Doctor

Strong Mother Strong Special Individual

Special needs individuals with mental disabilities and other special conditions accompanying mental needs (hearing disability, visual disability, physical disability, autism spectrum disorder, multiple disabilities, language and speech disorder, learning disability and emotional/behavioral disorder) are diagnosed with special needs individuals. It includes mothers who are in service. Caregivers of children with …

30 - 60 years of age Female Phase N/A

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