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Found 64,777 clinical trials
M Mark DeBoer, MD

AIDANET Pediatrics

AIDANET algorithm with smart-phone based control system (study smart phone), specifically modified Tandem insulin system (study insulin pump), and Dexcom G6 CGM (study CGM).

6 - 13 years of age All Phase N/A
J Jingdun Xie

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection. Therefore, we are conducting this prospective, randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP …

18 - 70 years of age All Phase 3
I IMPACT 170 Staff

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults (IMPACT)

The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk.

16 - 24 years of age All Phase N/A
K Kecia Keliiholokai

Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery

Perinatal mental health disorders are the most prevalent perinatal comorbidity and are associated with the primary cause of maternal mortality in the United States (US) - suicide. Diagnosis of a high-risk pregnancy and cesarean delivery (CD) are both associated with increased risk for perinatal mood, anxiety, and trauma symptoms (PMATS). …

years of age Female Phase N/A
A Amanda Gillespie, PhD

Deconstructing Voice Therapy: Towards Enhanced Communication Outcomes

This research study aims to evaluate the effect of treatment delivery method on voice outcomes over 12 months in people with a primary complaint of a voice problem, diagnosed with either non-phonotraumatic vocal hyperfunction, also known as primary muscle tension dysphonia (MTD) or phonotraumatic vocal hyperfunction, also known as benign …

16 - 65 years of age All Phase N/A
L Lydia Tang, MBChB

TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B

The goal of this clinical trial is to learn if HEPLISAV-B, a vaccine that is approved to prevent hepatitis B infection in people that are not already infected, is safe in people already chronically infected with hepatitis B. The main quiestions it aims to answer are: Is HEPLISAV-B safe in …

18 years of age All Phase 1

24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC

The purpose of this research is to study the effects and safety of alternating neoadjuvant chemotherapy on borderline resectable pancreatic cancer.

18 years of age All Phase 2
S Stephen C Orey, MS

Vascular Trial Associated Registry Pilot

The purpose of this investigator-initiated, multicenter, open label, randomized trial is to evaluate 1 month vs. 6 months of dual antiplatelet therapy (DAPT) in patients undergoing lower extremity endovascular revascularization. We hypothesize that extending dual antiplatelet therapy (DAPT) to six months, compared to one month, will improve patency rates of …

45 years of age All Phase 4
I Isaac Pascual Calleja, MD, PhD

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

To explore the impact of early transcatheter edge-to-edge repair of acute functional mitral regurgitation after myocardial infarction on the combined incidence of death and heart-failure associated hospitalisations at one-year follow-up, and quality of life and LV remodelling at two-year follow-up.

18 - 99 years of age All Phase N/A

Safety and Efficacy of Tarperprumig in Adult Participants With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis

The primary objective of this study is to evaluate the safety and tolerability of tarperprumig in participants with newly diagnosed or relapsing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.

18 - 80 years of age All Phase 2

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