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Found 64,776 clinical trials
W Wenjuan Xia

Remote Anxiety Management for ICS-resistant Asthma Study

This study, the Remote Anxiety Management for ICS-resistant Asthma Study (RAMICS), explores strategies to improve medication adherence and anxiety management in asthma patients who are resistant to using inhaled corticosteroids (ICS) due to anxiety. Asthma is a chronic respiratory disease affecting millions worldwide, and ICS therapy is essential for controlling …

18 - 80 years of age All Phase N/A
G Gamze Talih

Effect of Targeted Fluid Therapy on Postoperative Cognitive Dysfunction.

Postoperative cognitive dysfunction (POCD) describes a decline in cognitive function as measured by pre- and postoperative neuropsychological testing. It is common after cardiac surgery, affecting 25% to 70% of patients, and is usually associated with pathophysiological mechanisms such as cerebral hypoperfusion, cerebral microemboli, glycaemic control and neurotoxic effects of anaesthetic …

50 years of age All Phase N/A
L Laleh Zarrinkoob, MD, PhD

Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia

During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient blood flow to the brain. This project aims to map the relationship between blood pressure and brain blood flow using …

50 - 80 years of age All Phase N/A

A Clinical Study of ONO-1110 in Patients With Fibromyalgia

To Evaluate the Efficacy and Safety of ONO-1110 in Patients with Fibromyalgia

18 years of age All Phase 2
V Vivian Weiqun Lou, PhD

Holistic Self-Empowerment Care Intervention for Optimized Independent Living and Quality of Life: A Study Protocol

This protocol describes a pilot study evaluating the effectiveness of the Self-Empowerment Care Model in promoting independence and quality of life among frail older adults in Hong Kong. Rooted in Nordic re-enablement principles and refined in Japan, the intervention adopts a holistic approach that focuses on hydration, exercise, diet, and …

65 years of age All Phase N/A
H Hsiu Ying HSU, Master

Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy

Breast cancer ranks first in Taiwan's top ten gynecological cancers. Chemotherapy is a standard treatment method for colorectal cancer and breast cancer, but while destroying cancer cells, it also destroys healthy cells, resulting in side effects. Peripheral neuropathy can lead to peripheral nerve damage and decreased activity, which affects the …

18 - 80 years of age All Phase N/A
L Lung-Ji Chang, Ph.D

NG2 and DLL3 CAR-T Cells Targeting Melanoma

The purpose of this study is to assess the feasibility, safety and efficacy of multiple CAR-T cell therapy which targets NG2 and DLL3 surface antigens in patients with relapsed and refractory melanoma.

18 - 75 years of age All Phase 1/2
R Rachel Kingsford

Guided Meditation During Radiation Therapy for Brain Tumors

The goal of this interventional treatment study is to assess the anxiolytic effect of providing guided meditation during radiation treatment (RT) in patients with brain tumors. The main question it aims to answer is: • What is the change in acute anxiety in participants receiving the mindfulness intervention during radiation …

18 years of age All Phase N/A

Telmisartan in Prostate Cancer

The goal of this clinical trial is to learn about the tolerability of telmisartan in patients with prostate cancer, but evidence for treatment efficacy will also be gathered.

18 years of age Male Phase 1

Nature for Body Image

Nature exposure has been found to be particularly beneficial for body image, as recent studies have identified a positive association between time spent in nature and positive body image. Positive body image, defined as the ability to accept and respect one's body, has been linked to greater life satisfaction and …

18 - 35 years of age Female Phase N/A

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