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Found 65,447 clinical trials

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.

18 - 64 years of age All Phase 1
A Anders H Springborg, MD

Cryoneurolysis for Acute Postoperative Pain Following Total Knee Arthroplasty

Cryoneurolysis is a regional anaesthetic technique that works by freezing peripheral sensory nerves. This technique can potentially provide analgesia after total knee arthroplasty (TKA). However, the technique is expensive and comprehensive. Pain 24 hours after surgery is associated with high amounts of late acute pain. Therefore, the aim of the …

18 years of age All Phase N/A
D Dr Babu Lal Meena, DM Hepatology

Effect of Alternate Day Fasting Over Standard Medical Management Alone to Reverse Non-alcoholic Steatohepatitis.

The aims of this study are as follows: To compare the role of alternate-day fasting over standard medical management alone to reverse NASH.

18 - 65 years of age All Phase N/A

First-in-Human Trial of Oral AN2-502998

First-in-Human Phase 1, Single-Center, Randomized, Blinded, Placebo-Controlled Trial in Healthy Adults to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Oral AN2-502998

18 - 55 years of age All Phase 1
B Barış Çelik

The Effect of Surgical Incision Drep Use in Endotracheal Tube Fixation

It is aimed to minimise both unplanned extubation and skin damage with the surgical incision drep that we will use to fix the endotracheal tube in neonatal preterm infants and to reduce the complications that may develop due to these events. In addition, it is aimed to evaluate the relationship …

28 - 34 years of age All Phase N/A
D Dr. Eric Dippel, M.D.

FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW

This study is to assess the safety and efficacy of the FastWire System. It is intended to assess that the FastWire System can facilitate the intra-luminal placement of conventional guidewires or treatment devices beyond peripheral artery chronic total occlusions (CTOs)

18 - 85 years of age All Phase N/A
I Ingrid Zablith

Effectiveness of a Cognitive and Behavioral Treatment Program in People With Idiopathic Environmental Intolerance (IEI)

Idiopathic Environmental Intolerance (IEI) denotes a functional disorder represented by heterogeneous symptoms that sufferers attribute to specific environmental agents and for which there may be no solid evidence of an underlying physiological cause. We are conducting a randomized controlled trial study to compare patients before and after a newly developed …

18 years of age All Phase N/A
M Marjan Fathi, Suicidology, Postdoctoral

Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters

This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT). The study seeks to determine which of these two methods is more effective in reducing suicidal ideation and mental pain …

18 years of age All Phase N/A
S Stephen Wood, MD

Use Versus Non-use of Bladder Catheterization in Elective Cesarean Delivery

The goal of this randomized controlled trial is to investigate the impact of routine bladder catheterization in uncomplicated cesarean sections on hospitalization time (readiness to discharge), time to ambulation, urinary retention, development of urinary tract infections, prevention of bladder injury, operating time, and patient satisfaction.

18 years of age Female Phase N/A
J JESSIE HAWKINS, PhD

Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

This study evaluates the subjective effects of injection administration of NR on healthy adult populations.

40 - 65 years of age All Phase N/A

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