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Found 64,783 clinical trials

Effect of Multisensory Motor Imagery Training on Muscle Performance and Coordination in Children With Spastic Diplegia

PURPOSE The current study aims to: Determine the effect of multisensory motor imagery training on muscle performance including (peak torque, work, power) of trunk and knee flexors and extensors in children with spastic diplegia. Determine the effect of multisensory motor imagery training on coordination, strength and agility in children with …

8 - 12 years of age All Phase N/A
M Meili Sun, PhD.

A Study to Evaluate HB0034 in Healthy Chinese Adult Participants

The aim of this study is to investigate the safety and tolerability of HB0034 in healthy subjects following a single dose or multiple dose.

18 - 45 years of age All Phase 1
A Alyssa Avilez

Treatment of Myasthenia Gravis Exacerbation or Crisis With Efgartigimod

This study plans to learn more about if the drug efgartigimod can be used in the hospital to treat exacerbations in participants with myasthenia gravis (MG). Efgartigimod has been approved by the FDA for ongoing (chronic) treatment of generalized MG in adult patients who are anti-acetylcholine receptor (AChR) antibody positive …

18 years of age All Phase 4
I Irina V Greshnova

Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Ulcerative Colitis

The aim of the study is to evaluate the efficacy, safety, pharmacokinetics, pharmacodynamics and immunogenicity of study drug (BCD-261) in comparison with placebo and to characterize the dose-response relationship in patients with moderate to severe active ulcerative colitis. The study will be conducted in a population of male and female …

18 - 75 years of age All Phase 2
L Lise Aunsholt, MD, ph.d., professor

The NONA-LISA Trial

The NONA-LISA trial will be an investigator-initiated, multicentre, pragmatic, parallel-group, blinded RCT conducted at four university hospitals across Denmark. A total of 324 inborn premature infants will be included within 36 months at four neonatal intensive care units (NICUs) across Denmark (approximately 2 infants per month per unit). The aim …

24 - 30 years of age All Phase N/A

Effects of a Sedentary Behaviors at Work on Health in Emergency Medical Dispatchers and CODIS Operators (SECODIS)

The purpose of the study is to study changes in sedentary behavior following a behavioral intervention (sit-and-stand desk, and cycloergometer)

18 years of age All Phase N/A
J Jim Montgomery

Treating Complex Grammar Knowledge Deficits in School-Age Children With Developmental Language Disorder

The goal of this project is to compare the relative effectiveness of two novel treatments to improve the complex grammar knowledge of school-age (8-11-year-old) children with developmental language disorder (DLD). Treatment 1 is an implicit approach to promoting children's automatic grammar learning and Treatment 2 is a more conventional explicit …

8 - 11 years of age All Phase N/A
J Jennifer K Fairchild, PhD

Water-based Activity to Enhance Recovery in Long COVID-19

This two-year study will evaluate the feasibility and safety of an exercise + cognitive training program to improve neurological symptoms of long-COVID. This is a two-phased trial: 1) an exercise phase and 2) a cognitive training phase. The exercise phase will be an aquatic based exercise program. A combination exercise …

18 - 89 years of age All Phase N/A
C Cervical Ripening Balloon Study Coordinator

Cervical Ripening Balloons for Same-Day Cervical Prep

The goal of this clinical trial is to learn if a cervical ripening balloon (Foley balloon) works to prepare the cervix before same-day outpatient dilation and evacuation (D&E). The main questions it aims to answer are: Is cervical preparation with cervical ripening balloon for same-day outpatient D&E non-inferior to cervical …

18 years of age Female Phase N/A

Accelerated Theta Burst Stimulation for Treatment of Suicidality in Depressed Patients

The objective of this study is to investigate efficacy of accelerated theta burst stimulation (TBS) in suicidal reduction in patients with unipolar and bipolar depression

19 years of age All Phase N/A

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