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Found 64,776 clinical trials
A Audrey Lavoie, PhD candidate

Web-based Nursing Intervention to Promote Physical Activity Among Older Adults With Coronary Heart Disease

The purpose of this study is to develop and evaluate a web-based nursing intervention aimed at increasing physical activity in people aged 65 years and older with coronary heart disease. This study aims to answer the following questions: What are the needs of older adults living with coronary heart disease …

65 years of age All Phase N/A

Effectiveness of Brief Mindfulness-Based Interventions for Painful Temporomandibular Disorders Among University Students

The goal of this clinical trial is to learn if brief mindfulness-based intervention (BMBI) is beneficial to participants suffering from painful temporomandibular disorders (TMD). The objectives of the research are: To compare physical functioning (pain intensity and jaw function) in UM students with chronic pain-related TMD before and after receiving …

18 - 30 years of age All Phase N/A
R Rebecca Cox, PhD

Light Therapy for Obsessive-compulsive Disorder (OCD)

The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later). The main question[s] it aims to answer are: Does light therapy reduce OCD symptoms? Does light therapy advance the circadian clock? If …

17 - 35 years of age All Phase N/A
E Erin Laurie-Zehr, MA

Promoting Resilience in Women With Breast Cancer (PRISM -MBC)

This pilot interventional study evaluates the change from baseline to post-intervention in resilience and other patient-reported outcomes for individuals with a recent diagnosis of metastatic breast cancer (MBC) participating in the Promoting Resilience in Women with Breast Cancer (PRISM) intervention, overall and stratified by race, and to evaluate the feasibility …

18 years of age All Phase N/A
e emine arıcı parlak

The Effect of the Operating Room Environment on Patients Experienced With Virtual Reality Glasses Before Surgery

This study was planned as a randomized controlled experimental study with a pretest-posttest design to examine the effect of the operating room environment experience of preoperative patients using virtual reality glasses on the patients' preoperative surgical fear level and care perceptions.

years of age All Phase N/A

Mechanisms Underlying the Efficacy of Prolonged Exposure

The primary objective of this research is to collect pilot data that demonstrates that proposed neural, psychophysiological and subjective markers measured before, during, and after treatment change over the course of Prolonged Exposure therapy (PE) for posttraumatic stress disorder (PTSD). The aims of the study are to: (1) examine theoretically …

18 - 90 years of age All Phase N/A
q quchang ouyang

A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

This study is a multicenter, open-label, randomized controlled, Phase 3 clinical trial.

18 - 75 years of age Female Phase 3
C Cyndi Holland, MPH

Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

The primary objective of this multi-site randomized clinical trial (RCT) is to compare Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) with usual care vestibular rehabilitation (VESTIB CONTROL) in 250 individuals with mTBI-related vestibular symptoms attributable to mild traumatic brain injury (mTBI) treated at one of two sites (1) the …

18 - 49 years of age All Phase N/A

Evaluation of Full Veneered Porcelain-Fused-to-Metal Crowns Cemented With Self-Adhesive Resin Cement Using Two Curing Modes

P - Population/Patient Problem Adult patients requiring full coverage porcelain-fused-to-metal (PFM) crown restorations I - Intervention PFM crowns veneered with porcelain system cemented using self-adhesive resin cement in DUAL-CURED mode (light-cured for 20 seconds per surface) C - Comparison PFM crowns veneered with porcelain system cemented using self-adhesive resin cement …

21 years of age All Phase N/A
M Marilyn Rothen

Topical 10% Povidone-Iodine in Preventing White Spots

The goal of this clinical trial is to learn if topical application on the all surface of 10% Povidone Iodine (Povi-One) in healthy participants in transitional or permanent dentition (10-17 y) prevents new white spot lesions in the maxillary anterior teeth at 1 year of follow-up. Researchers will compare Povi-One …

10 - 17 years of age All Phase 2

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