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Found 64,776 clinical trials
H Han Gil Seo, MD, PhD

Self-administered tDCS for Improving Single- and Dual-task Gait in Patients With PD

The purpose of this study is to investigate the efficacy and safety of self-administered transcranial direct current stimulation to improve the single- and dual-task gait in patients with Parkinson's disease.

19 years of age All Phase N/A
J Jesse Hill

Optimal Number of Hyperbaric Oxygen Treatments for Carbon Monoxide Poisoning

The optimal treatment strategy with hyperbaric oxygen therapy has been the subject of some debate over the past 3 decades. Initial landmark studies showed a decrease in the incidence of DNS with a single treatment and also with three treatments over the course of 24 hours. These two strategies have …

17 years of age All Phase N/A
S Sae-Yeon Won

Strokectomy in Malignant Cerebral Media Infarction

Decompressive hemicraniectomy (DC) is the standard procedure and life saving measure in case of malignant middle cerebral artery (MCA) infarction. However, there have been several studies reporting the neuroinflammatory cascade based on the necrotic tissue as one of the leading cause for the secondary brain damage, wherefore, strokectomy with resection …

18 years of age All Phase N/A
Z Zhijun Dai, Professor

Neoadjuvant Chemotherapy Plus Pyrotinib and Trastuzumab for HER2-positive Breast Cancer (NEOTORCH-BREAST05)

This study is a prospective, single arm, multi-center clinical trial. The primary study objective is to evaluate the pathologic complete response (pCR)and clinical complete response(cCR) of neodjuvant treatment of HER2-positive breast cancer with pyrotinib and trastumab combined with neoadjuvant chemotherapy. The secondary study objective is to observe and evaluate the …

18 - 75 years of age Female Phase 2
D David Mataix-Cols, Professor

ICBT for OCD in Children With Autism

The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder (OCD) in children and adolescents with autism. A process evaluation of the treatment will also be conducted.

7 - 17 years of age All Phase N/A

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

A Study of the Anti-CD 19 Chimeric Antigen Receptor T Cell Therapy for Patients with Myasthenia Gravis

18 - 75 years of age All Phase 2/3
H Hervé Schlotterbeck, Medical Doctor

Effect of Virtual Reality on Patient's Comfort During Cardiac Electronic Device Implantation.

The purpose of this study is to assess the effect on patient's comfort of a virtual reality experience during a procedure of cardiac electronic device implantation under local anesthesia.

18 years of age All Phase N/A
P Patricia Casas, PhD

The Effect of Chlorhexidine Mouthwash on Postprandial Glucose Response in Healthy Individuals

The digestion of carbohydrates begins in the mouth through the salivary enzyme amylase which breaks food starches into maltose and disaccharides. The mouth also has a large community of microorganisms which include bacteria, fungi, viruses and protozoa that can also assist in the digestion of carbohydrates. Mouthwashes containing antibacterial compounds …

18 years of age All Phase N/A
Q Qasir Abbas, PhD

4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) Among Young Adults

The goal of this clinical trial is to develop a comprehensive Training Program intervention for social media addiction called the 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and to learn if the 4-STEP-TPS will address and help manage the problems related to social media addiction. Other key objectives include the …

18 - 30 years of age All Phase N/A
D David Hui

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

To examine the effects of haloperidol, chlorpromazine, valproic acid and placebo, in conjunction with standardized non-pharmacologic interventions, in the first line treatment of agitated delirium in hospitalized patients with cancer. This double-blind, randomized clinical trial aims to provide evidence on various therapeutic options for palliating delirium, thereby reducing delirium-related distress …

18 years of age All Phase 2/3

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