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Found 64,776 clinical trials
S Sheila Kelly, MPH

Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person Vs. ONline

The goal of this study is to evaluate the effectiveness of CHAMPION ("Comparative-effectiveness of a Healthy lifestyle and Asthma Management Program, In-person vs ONline"), a primary care-based intervention to address childhood obesity and asthma, and test the effectiveness of a telehealth-only version of the program. Intensive Health Behavior and Lifestyle …

6 - 17 years of age All Phase N/A
K Kina Bennett

Enteral Feeding of Fibre to Improve Microbiota

Following surgical removal of diseased bowel, patients often require a temporary redirection of bowel contents to a stoma, to allow healing prior to re-joining of the remaining bowel at a later date. Some patients may experience complications, either during or after reversal surgery, and this may be due to changes …

18 years of age All Phase N/A
T Tobias Bomholt, MD, PhD

Continuous Glucose Monitoring in Dialysis Patients With Diabetes

The primary objective of this multicenter, randomized controlled trial is to assess whether the intermittent or continuous use of continous glucose monitoring can enhance glycaemic control among dialysis patients with type 1 or type 2 diabetes, in comparison to the standard monitoring involving finger-prick glucose and HbA1c. Participants will be …

18 years of age All Phase N/A
N Nora ALLOY, MD

Clinical Trial Evaluating Secondary HPV Vaccination After Treatment of High-grade Cervical Lesions

This is a single-center, Phase II interventional study evaluating secondary HPV vaccination after treatment of high-grade cervical lesions. The study aims to estimate the rate of HPV clearance within two years following an initial positive HPV control test in women over 45 years of age who are chronic HPV carriers …

45 years of age Female Phase 2
R Rebecca Rochowiak

Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age

Dravet syndrome is a genetic epilepsy associated with pathogenic variants in SCN1A that codes for Nav1.1, a protein necessary for sodium channels. Children with Dravet syndrome classically present in the first year of life with prolonged seizures, often hemiclonic and in the setting of fever or temperature changes such as …

12 - 24 years of age All Phase 4
S Stuart Clare, PhD

Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation

Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training. However, responses to classical NIBS protocols are highly variable. Movement-related changes in specific brain rhythms have previously been shown to be …

18 years of age All Phase N/A
M Malakah Mohamed, secretary

Thulium Beam Coagulation Versus Suture Renorrhaphy for Hemostasis of Tumor Bed in Laparoscopic Partial Nephrectomy

To compare the outcome of thulium beam coagulation versus suture renorrhaphy for hemostasis of the tumor bed in laparoscopic partial nephrectomy.

16 years of age All Phase N/A
S Sonia Fargue, PhD

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones …

18 - 80 years of age All Phase N/A
W Waleed Elmallah, PhD

Postoperative Pain After Activation of Irrigant

The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation techniques, negative pressure irrigation technique and traditional irrigation techniques. PICOTS Question: Does the …

18 - 50 years of age All Phase N/A

Effect of Attentional Therapy on Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder. We recently showed using eye-tracking evidenced two types of AB towards negative stimuli: a "physiological AB" found both in healthy and individual with …

18 - 60 years of age All Phase N/A

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