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Found 64,783 clinical trials

Comparative Effects of Traditional Play and Free Play in Primary School Children

Childhood play is crucial for the comprehensive development of children, as it fosters social and emotional skills. This study examines the relative effects of conventional games versus unstructured play on the social interaction and physical fitness of elementary school students. This study aims to explore the impact of traditional games …

5 - 9 years of age All Phase N/A
A Amanda Prieur

Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet Drugs

This study will identify the potential benefits of regulating platelet activation with sotagliflozin compared to other FDA-approved drugs known to limit platelet activation.

18 - 79 years of age All Phase N/A
J Jianhua Mao, MD

Study of Therapeutic Efficacy of CAR-T Cell Therapy in Patients With MDR-SRNS

This is an investigator-initiated trial aimed at assessing the safety and efficacy of anti-BCMA/CD70 CAR-T cells in the treatment of patients with Multi-drug resistant SRNS

2 years of age All Phase 1
a alem coşgun

The Effect of Different Deproteinising Agents on the Clinical Success of Fissure Sealants in Permanent Teeth

Investigation of the effect of deproteinization agents on the clinical success of non-invasive fissure sealant application, which is a non-invasive method used to prevent caries formation or to stop the progression of initial caries lesions limited to enamel on tooth surfaces thought to be at high risk of caries.

6 - 9 years of age All Phase N/A
K Katherine Pennycott, RN

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

This is a study designed to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of WEF-001 as monotherapy in patients with Advanced KRAS-mutant solid tumours.

18 years of age All Phase 1/2
M Mariam MA Elsebaey, PhD

Comparison of Perforated 3D Printed Versus Conventional Metal Fixed Bonded Retainer

Although different materials of mandibular fixed retainer were discussed in the literature, there is contradicting evidence regarding the bond failure of Titanium fixed metal retainer, whether immediate or after 12 months. Moreover, insufficient evidence is present regarding 3D metal printed fixed mandibular retainers.

15 - 35 years of age All Phase N/A
Q Qurat ul Ain Saeed, MS-OMPT

Additional Effects of Dry Needling With Conventional Physical Therapy Versus Conventional Physical Therapy in Plantar Fasciitis: a Randomized Control Trial

This study is a randomized controlled trial and the purpose of this study is to determine the effects of dry needling with conventional physical therapy versus conventional physical therapy on gait parameters in plantar fasciitis: a randomized control trial.

18 - 35 years of age All Phase N/A
M Mickael PREAULT, Dr

Reintegrating a Systematic Review Consultation With the General Practitioner After the Cancer Diagnosis Has Been Announced Into the Complex Cancer Patient Pathway: Feasibility Study

This is a prospective, multicentric, regional study designed to assess the feasibility of setting up a summary consultation with a general practitioner (GP) to complement the consultation for the announcement of a cancer diagnosis. 171 patients will be included in the study. Each patient will be followed for 6 months.

18 years of age All Phase N/A
J Jing Zhang, Docter

Trial of JMKX003801 in Healthy Participants

To Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of JMKX003801 Administered Randomly, Double-blind, Placebo-controlled, Single-ascending Dose and Multiple-ascending Dose in Chinese Healthy Adult Participants

18 - 45 years of age All Phase 1
x xiaosong chen, director

Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma

Melasma is a refractory skin disease with a complex pathogenesis and difficult treatment. Research has found that mesenchymal stem cell-derived exosomes have effects such as anti-wrinkle formation, anti-inflammation, antioxidant properties, skin whitening, and promotion of skin regeneration. Recent studies show that there is damage to the basement membrane in melasma …

18 - 60 years of age All Phase N/A

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