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Found 65,447 clinical trials

Study of ZG005 in Combination With Paclitaxel+Platinum-based ± Bevacizumab in Patients With Advanced Cervical Carcinoma

This is a multicenter, open-label phase I/II study for the first-line treatment of advanced cervical cancer.

18 - 70 years of age Female Phase 1/2
P PIÑERO PINTO, PhD

The Coping With and Caring for Infants With Special Needs Intervention in Down Syndrome Infants

The objective is to compare the impact of standard infant physical therapy and the family-centered program, Coping with and Caring for Infants with Special Needs (COPCA), on infants born with Down syndrome. This is a randomized controlled trial that will be carried out in the patients' homes and outpatient settings …

1 - 18 years of age All Phase N/A
M Marc FARAGGI, MD-PhD

Strategy for Unstable Coronary Plaque in Patients Presenting to Emergency Department for Chest Pain Suspected of Coronary Artery Disease

Primary prevention of coronary disease and especially its major complication, inaugural myocardial infarction, is based on any prodromal symptoms identification and on risk profile establishment. About 50% of myocardial infarctions are caused by an unstable non-stenosing plaque, asymptomatic before the event since without significant reduction in coronary flow, particularly during …

18 - 79 years of age All Phase N/A
G Ghaith J Androwis, Ph.D.

The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI

To evaluate the usefulness of an upper extremity assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury. The Department of Defense is supporting this study.

18 - 80 years of age All Phase N/A
Y Yucel Can Danisman

Effect of Virtual Reality Glasses on Anxiety During Cystoscopy: A Randomised Controlled Trial

The aim of this study was to investigate the effect of using virtual reality glasses as a distraction method on anxiety in men undergoing cystoscopy under local anaesthesia.

18 years of age Male Phase N/A

Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults

This study aims to generate clinical data on the efficacy, safety, and tolerability of rezafungin combined with 7 days of co-trimoxazole for treatment of Pneumocystis pneumonia (PCP) in adults living with human immunodeficiency virus (HIV), which would expand the knowledge of clinical use of rezafungin.

18 years of age All Phase 2
Y Yong Lin, MD

Driving Pressure-guided Lung Protective Ventilation

The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving pressure-guided lung protective ventilation can reduce postoperative oxygenation function in patients who have undergone surgical repair of acute …

14 - 70 years of age All Phase N/A
X Xu Li, Doctor

A Study of the Efficacy of Troxerutin in Preventing Thrombotic Events in COVID-19 Patients

The goal of this clinical trial is to learn if troxerutin works to prevent thrombotic events in mild or severe COVID-19 patients. It will also learn about the safety of troxerutin. The main questions it aims to answer are: Does troxerutin lower the number of thrombotic events in participants? What …

18 years of age All Phase 1
S Sonia Fargue, PhD

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy …

18 - 70 years of age All Phase N/A
L Laura López-García

Effectiveness of Massage of the Thoracic Region in Neck Pain

Neck pain is a common disorder in industrialized countries. Manual therapy techniques have been commonly used in the treatment of this problem. Actually, there is no research work that has evaluated the work well of treatment with soft tissue techniques (massage) applied to the dorsal paravertebral muscle in the management …

18 - 70 years of age All Phase N/A

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