Found 64,776 clinical trials
SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer（SPARKLE）
This is a prospective study to delve into the therapeutic benefits of combining stereotactic body radiation therapy (SBRT) with PD-1 monoclonal antibody treatment for patients with unresectable locally recurrent rectal cancer (ULRRC). Our aim is to ascertain the safety of this approach and to offer robust, evidence-based medical guidance for …
Kinesio Taping Effects on Balance and Ankle Proprioception
Ankle injuries are among the most common musculoskeletal injuries, affecting both athletes and the general population. Various methods are used to prevent such injuries, but the effectiveness of different kinesio taping applications on joint position sense and balance remains unclear. This study aims to investigate the effects of different kinesio …
The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home
It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research. The research population consists of elderly people living alone at home who are registered to the Elderly and …
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
People with type 1 diabetes sometimes develop heart failure which can cause symptoms like breathlessness, tiredness or ankle swelling, reduced quality of life and lead to being admitted to hospital or suffering potential fatal consequences. This trial is investigating if a tablet called sotagliflozin, can improve quality of life in …
Meditative Neurofeedback for Depression
The goal of this open-label single-arm study is to test a meditative neurofeedback intervention for depressed mood.
Fast Track to Fertility
The Fast Track to Fertility (FTF) program is an algorithmic text messaging communication and patient education platform designed to improve the efficiency the fertility workup. The initial pilot program resulted in an approximately 50% reduction in the time taken to complete the diagnostic workup. Since the pilot program, the investigators …
Placebo Impacts Sleep and Pain Modulation in Chronic Pain
The goal of this free-choice parallel design clinical trial is to examine the potential beneficial effects of using open-label placebo (OLP) in improving chronic pain related outcomes and sleep quality in people with temporomandibular disorders. This study will enroll a cohort of participants with temporomandibular disorders (TMD) which lasts for …
UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy
Patients with graft failure or delayed engraftment may benefit from a hematopoietic stem cell boost or an additional hematopoietic stem cell transplantation procedure. In such settings standard immune suppression strategies are avoided due to their myelosuppressive nature. Therefore those patients are at increased risk of graft versus host disease, and …
Using Simplified Meal Boluses Versus Carbohydrate Counting in Adolescents With Hybrid Closed Loop Systems
The goal of this trial is to evaluate blood sugar control in patients with type 1 diabetes when using a simple meal bolus strategy (small, medium, large meals) compared to carbohydrate counting when on a hybrid closed loop system. The main question it aims to answer are: What is the …
A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC
This study aims to explore the efficacy and safety of the combination therapy of utidelone and capecitabine in the treatment of brain metastases from triple-negative advanced breast cancer, and to search for systemic treatment for brain metastases from triple-negative advanced breast cancer cases.
