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Found 64,783 clinical trials
P Pejman Sehatpour, Ph.D.

Temporal Interference Stimulation for Social Cognition

The long-term goal of this project is to evaluate whether a procedure termed transcranial interference stimulation (tIS) may be useful in the future in the treatment of severe neuropsychiatric disorders such as schizophrenia. The purpose of this stage of the project is to evaluate the safety and tolerability of tIS …

18 - 55 years of age All Phase N/A
A Aristotle University

Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry

Aim The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or without the application of tetracycline slurry. Research Hypothesis: The hypothesis is that the adjunctive application of tetracycline slurry …

18 years of age All Phase 4
M Mohamed I Elmaadawy, MD

Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture

This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.

18 years of age Male Phase N/A

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

The goal of this clinical trial is to learn about the safety and efficacy of a potential new treatment called Lenti-HPV-07 in patients with a cancer induced by Human Papilloma Virus (HPV). The main questions aim to answer are: Is Lenti-HPV-07 safe? Does Lenti-HPV-07 induce an immune response? Participants will …

18 years of age All Phase 1/2
N Nathalie Robert, DDS

Comparison of Conventional Impressions, Intraoral Scanners and Digital Photogrammetry for Full-arch Implant Prosthesis.

The aim of this clinical trial is to compare implant-supported definitive impressions in edentulous patients (mandible or maxilla) with 4 to 8 osseointegrated implants. The main questions it aims to answer are : The primary outcome of this prospective clinical comparative study is to analyse the precision of a complete-arch …

18 years of age All Phase N/A
G Gwynne Mhuireach, PhD

Garden-fresh Foods and Gut Microbiomes

The purpose of this research is to explore what types of microbes are present on garden-fresh versus store-bought fruits and vegetables, as well as how they might affect the human gut microbiome.

18 - 45 years of age All Phase N/A
F Fatma Soliman E Ebeid

Serratus Anterior Plane Block and Costotransverse Block for Analgesia Following Modified Radical Mastectomy Surgeries

Adequate pain management following modified radical mastectomy (MRM) is crucial for early ambulation and patient satisfaction. Breast cancer is the most common malignancy in females, with an increasing incidence in recent years. Surgery is one of the mainstays of therapy for breast cancer, and modified radical mastectomy (MRM) is the …

18 - 60 years of age Female Phase N/A
M Monica Perez, PhD, PT

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used twice-daily in combination of Spike-timing-dependent plasticity (STDP) stimulation and STDP stimulation with limb training.

18 - 85 years of age All Phase 1/2
R Rongqi Bei

Supporting Care Partners' Well-Being With Artificial Intelligence (AI) Chatbots

This study is being completed to test an AI therapy chatbot application called Earkick to see whether it is feasible and acceptable in supporting care partners who support individuals living with dementia.

18 years of age All Phase N/A
K Kandice Motley, BS

Clinical Evaluation of Montelukast in Veterans With Gulf War Illness

The study addresses the pre-clinical promise of Montelukast (MLK) for improving brain function in veterans with Gulf War Illness (GWI). MLK, a US Food and Drug administration (FDA)-approved drug for asthma, has shown efficacy in an animal model of GWI to improve cognitive and mood function through modulation of leukotriene …

50 - 70 years of age All Phase 1

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