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Found 65,447 clinical trials
A Alice MANNOCCI, PhD

Giochiamo 626 - Gaming for Health and Safety in Workplaces

The aim of the "626 Giochiamo" project is to realise and evaluate the effectiveness of a training course involving the use of games, which helps to convey the basic principles of health and safety in the workplace.

17 - 69 years of age All Phase N/A
İ İnci H Ayas

Gait Pattern Analysis After All Arthroscopic ATFL Repair Surgery

The study will investigate alterations in post-surgical gait patterns among patients who have undergone all arthroscopic repair surgery for the anterior talofibular ligament (ATFL) due to ankle instability. The gait biomechanics of patients scheduled for surgery will be assessed preoperatively using pedobarographic analysis. Subsequent changes in walking biomechanics will be …

18 - 65 years of age All Phase N/A
J Joseph Makhema, MD

Tshireletso: Safety, Efficacy and Feasibility of Cabotegravir-LA PrEP in a Breastfeeding Population in Botswana

The goal of this this hybrid safety/implementation study is to evaluate whether using long-acting cabotegravir (CAB-LA) for HIV prevention (PrEP) is acceptable, feasible and safe in post-partum people who are breastfeeding. The main question[s] it aims to answer are: Will CAB-LA injections work well as a way to prevent HIV …

18 years of age Female Phase 4

Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury

Aim 1: Determine the safety and feasibility of administration of TSCS to children in a clinical setting. Participants will be randomly assigned to experimental (TSCS) or control (sham stimulation) groups. Both groups will receive eight-weeks of individualized gait training. We will measure adverse events, including pain and skin irritation, to …

3 - 16 years of age All Phase N/A
M Mohamed Ezzelregal Abdelgawad

Heat Strain Prevention in Elderly Agricultural Workers

The study explores a multi-component heat strain prevention program for older agricultural workers in response to climate change. It assesses hydration, rest breaks, reflective clothing, and shade provision. Utilizing a quasi-experimental design, it targets 120 elderly workers, evaluating core temperature, heart rate, and heat strain symptoms. The goal is to …

60 - 90 years of age All Phase N/A
M Maja Guberina, PD Dr. med. (MD), specialist

Adaptive Radiotherapy in Head and Neck Tumor Patients

Most newly diagnosed oropharyngeal and hypopharyngeal cancers are treated with radiochemotherapy with curative intent. If the field-set UP margins are broad, the consequence may be that quality of life is impaired. The study group of Nutting et al. (2023) investigated this year whether dysphagia-optimized intensity-modulated radiotherapy can reduce the radiation …

18 years of age All Phase N/A
I Ine Lowyck, MD

Telemonitoring of Pregnancies Complicated With Gestational Diabetes Mellitus.

This interventional study examines the addition of telemonitoring (TM) in prenatal care for gestational diabetes mellitus (GDM). By incorporating TM into the prenatal care for GDM, it is expected to achieve faster and improved follow-up, resulting in faster reaction time in the detection of aberrant blood glucose levels. Therefore, the …

18 years of age Female Phase N/A
P Pengchao Li, PhD

Comparison of the Application of Robot-assisted Laparoscopic Pathways in Radical Cystectomy

Traditional radical cystectomy (RC) is performed transabdominal. However, it often has high postoperative complications. There have been studies on extraperitoneal approach to reduce postoperative complications. Investigators divided participants underwent robot-assisted radical cystectomy into two groups (1:1) . One group of participants transabdominal, the other group extraperitoneal. The incidence of complications …

18 - 75 years of age All Phase N/A
K Katarzyna Jerzak, MD

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

The goal of this multi-centre, prospective study is to assess the frequency of asymptomatic brain metastasis in patients with stage II or III Triple Negative or HER2 positive breast cancer. The main questions it aims to answer are: What proportion of patients with stage II or III Triple Negative or …

18 years of age All Phase N/A
F Flora Danquah

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

The purpose of this study is to assess and compare GI toxicity from RT between subjects who receive therapeutic SCFA and those who receive placebo, in hopes of identifying a safe, low-cost therapeutic to reduce GI toxicity from therapeutic or environmental radiation.

18 years of age All Phase 1/2

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