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Found 65,447 clinical trials

Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study

This phase II study will evaluate dostarlimab with a watch-and-wait approach for patients with localized mismatch repair deficiency (dMMR)/microsatellite instability (MSI) gastric or oeso-gastric junction adenocarcinoma. The goal of the study is to determine whether the surgery could be avoided in patients with localized dMMR/MSI-H gastric/OGJ adenocarcinoma with complete response …

18 - 75 years of age All Phase 2

Combined Kinetic Chain Exercises on Knee Osteoarthritis

study will be conducted at faculty of physical therapy cairo university to investigate the effect of combined kinetic chain exercises on static and dynamic hamstring and quadriceps strength in knee osteoarthritis patients

38 - 65 years of age All Phase N/A
B Belaïd Bouhemad

Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)

The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.

18 years of age All Phase N/A
J Jennifer L Reed, PhD

An Evaluation of the Talk Test for Exercise Prescription for Home-Based Cardiac Rehabilitation

The objectives of this pilot RCT are to examine if the Talk Test is an effective and safe tool as compared with CPET for exercise prescription in patients who have undergone CABG or PCI and enrolled in a home-based CR program with virtual exercise training monitoring.

40 years of age All Phase N/A
M Musa Yilmaz, MD

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

This phase I/II trial studies how well quizartinib, decitabine, and venetoclax work in treating participants with acute myeloid leukemia or high risk myelodysplastic syndrome that is untreated or has come back (relapsed). Quizartinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. …

18 years of age All Phase 1/2

Preventing Gastrointestinal Disturbance in Patients After Longitudinal Laparotomy.

This is a multi-center, randomized, double blind, placebo-controlled, phase 2 pilot efficacy study.

18 - 75 years of age Female Phase 2
Y Ying Song, M.D.

Outcome of 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism

To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)

18 - 70 years of age All Phase N/A
N Nancy Lau, PhD

Resilience Mobile App for Teens and Young Adults With Cancer

The goal of this pilot trial is to examine whether a mobile app version of the Promoting Resilience in Stress Management (PRISM) intervention is acceptable, easy to use, and helps improve quality of life and mental health symptoms.

12 - 25 years of age All Phase N/A
Y Yiming Zhao, M.D.

Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)

The goal of this clinical trial is to compare the PCR rate between Total Neoadjuvant Treatment ±Immunotherapy in high risk locally advanced rectal cancer. The main questions it aims to answer are: The PCR rate between the two groups The 3years DFS between the two groups Chemoradiotherapy and immunotherapy toxicity …

18 - 75 years of age All Phase 3
F Farhana Raduan, MS

Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease

The goal of this observational, practice-based feasibility study is to observe the efficacy and safety of intramuscular administration of Stempeucel® in Malaysian patients with critical limb ischemia (CLI) due to Buerger's disease. The main questions it aims to answer are: Can intramuscular administration of Stempeucel® reduce symptoms of CLI due …

18 - 65 years of age All Phase 4

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