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Found 65,447 clinical trials
J Jingbo Wang, Dr.

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

This trial aims to evaluate whether the addition of anti-PD-1 antibody to adjuvant postoperative chemoradiotherapy could improve disease free survival in patients with high-risk locally advanced head and neck squamous cell carcinoma (HNSCC).

18 - 70 years of age All Phase 2
C Carisa Cooney, MPH,CCRP

Human Penile Allotransplantation

Injuries to the genitalia are of concern to the military with emphasis placed on the surgical reconstruction and psychological health of these Wounded Warriors. However, despite significant surgical advances in microvascular surgery and autologous free tissue transfer, conventional reconstructions cannot truly replace the complicated structures and functions of the penis …

18 - 69 years of age Male Phase 2/3

RCT for the Efficacy of Soothing Cream Jel in Improving Upper Limb Pain and Motion

This is a randomized, double-blinded, placebo-controlled clinical trial. This trial is used to evaluate the efficacy of soothing cream jel on chronic upper limb pain and the range of motion.

18 - 60 years of age All Phase 2
U Ulrica Gidlund, DDS

Oral Health in Patients With Severe Eating Disorders

The overall aim of the research project is to assess whether the quality of life of patients with severe eating disorders is improved by dental treatment. Patients diagnosed with anorexia nervosa, bulimia nervosa or non-specific binge eating disorder with extensive dental treatment need will be treated with resin composite restorations …

18 - 50 years of age All Phase N/A

Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa

After confirming eligibility, a single subject with four selected target lesions will receive both ALLO-ASC-SHEET and Vehicle control, three target lesions for ALLO-ASC-SHEET and the other target for Vehicle control, and which lesion to apply which IP treatment will be determined randomly at the time of enrollment using pre-designed block …

4 - 60 years of age All Phase 2
Q Qixun Chen

Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC

To observe the 1-year disease-free survival rate (1-year PFS) of patients with resectable esophageal squamous cell carcinoma who received neoadjuvant chemoradiotherapy combined with camrelizumab and achieved clinical complete remission with watchful waiting strategy.

18 - 75 years of age All Phase 2
D Daniel Kleissler

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy. The secondary objective is to evaluate the feasibility of using the D3-creatine dilution method (D3Cr) to measure skeletal …

8 - 21 years of age All Phase N/A
S Stephanie Papas, MPH

Healthy Homes Study

This study is about home air radon testing and has two phases. The goal of the first phase is to learn about renters' and homeowners' views and plans related to radon testing. The main question this phase aims to answer is: Does taking part in a focus group with information …

18 years of age All Phase N/A
A Adela Escandon-Cesarman, Medical degree

Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Older Adults

Cognitive impairment is one of the fastest growing diseases in the last decades, given the significant increase in senior citizen population in Mexico and the world. Several studies have discussed the gut-microbiota-brain axis. It has been demonstrated that a balanced gut microbiota, prevents an increase in pro-inflammatory cytokines that affect …

70 - 85 years of age All Phase N/A
P Paul Allen

Human Visual and Vestibular Motion Perception Study

The purpose this study is to measure sensitivity to visual and vestibular or balance motion. It is hoped that the results may help researchers better understand how aging and disease affect motion perception.

18 - 80 years of age All Phase N/A

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