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Found 65,447 clinical trials

Single Session Narrative Therapy Study

This pilot research study will provide timely access to behavioral health services through the provision of a single-session narrative therapy intervention. The goal of this 6-month study is to test the acceptability, feasibility, and fit of the intervention in an integrated primary care clinic serving people living with HIV.

18 years of age All Phase N/A

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

The purpose of this study is to find out about the safety and how well the study intervention (elafibranor) works in participants with PBC. The participants in this study will have confirmed PBC with inadequate response or intolerance to UDCA, which is a medication used in the management and treatment …

18 - 75 years of age All Phase 3

Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

A Phase I modular study to assess the effect of oral saruparib on other treatments in patients with advanced solid malignancies.

18 years of age All Phase 1
W Wei Zhang

Exploratory Study on the Role of Vitamin C in Promoting Health in Middle-Aged and Elderly Adults

The purpose of this clinical trial is to understand whether oral vitamin C can help delay the aging of middle-aged and elderly individuals, search for sensitive biomarkers of human aging, and provide new paradigms and scientific guidance for aging intervention with small molecule drugs. The main questions it aims to …

18 - 70 years of age All Phase N/A
w wenying wu

Research on the Application of CARE Combined With AIDET Nurse-Patient Communication Model in Implementing Service Remediation in Outpatient Clinics

CARE (C: connect, A: apologize, R: repair, E: exceed) is a standard service recovery communication mode in medical services. However, clinical nurses found it hard to follow because it lacked essential communication guidance. The AIDET mode (A: acknowledge, I: introduce, D: duration, E: Explanation, T: thank), which offers such guidance, …

years of age All Phase N/A
H Huizhen Jin

Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III

This trial employs a multicenter, randomized, open-label, standard-of-care-controlled design and plans to enroll 50 patients with Type 2 SMA aged 2 to 12 years who have previously received nusinersen. The primary objective of the trial is to evaluate the efficacy of GC101 in treating Type 2 SMA. The secondary objectives …

2 - 12 years of age All Phase 3

A Clinical Study of SPH9788 Tablets in Healthy Chinese Subjects.

The purpose of the study is to evaluate the safety of SPH9788 tablets in healthy subjects.

18 - 45 years of age All Phase 1
G Gilmar M Santos, PhD

Myofascial Reorganization on Performance, and Biomechanical, Viscoelastic, and Thermographic Properties of Athletes

This is a two-group randomized clinical trial (includes an experimental and a placebo group) to verify the effects of the Myofascial Reorganization (RMF) compared to the placebo-RMF technique on running performance and thermographic, biomechanical, and viscoelastic proprieties of lower limbs of male triathletes. Data collection will be carried out one …

18 - 45 years of age All Phase N/A
P Pat Principal Quillen

Classroom Break, Cognition, and Fitness in Elementary School Children

The goal of this randomized controlled trial is to learn about the effect of a 12-week school-based intervention combining mindfulness with high-intensity interval training (MF-HIIT), MF-only intervention, and HIIT-only intervention in relative to sedentary activities on executive function (EF) in 8-12 years old children. The main question it aims to …

8 - 12 years of age All Phase 1/2
M Maria Cristina Meriggiola, MD, PhD

Evaluation of Sarcopenia in Women in Different Stages of Life and in Hormonal Therapy or Not

The three-year interventional study has the following objectives: The study aims to assess the prevalence of sarcopenia in menopausal women receiving hormone replacement therapy or not compared with pre-menopausal women. The study population will be divided into groups according to the intake or not of hormonal therapy of menopause as …

18 - 65 years of age Female Phase N/A

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