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Found 64,772 clinical trials
D Doreen Schmidl, MD, PhD

The Trial is a First-in-human, Phase I, Open-label, Dose-escalating Trial to Assess the Safety and Tolerability of ES2B-C001 Combined with Montanide or Without Montanide, in Patients with Human Epidermal Growth Factor Receptor 2 (HER2) Expressing Metastatic Breast Cancer

The trial is a first-in-human, phase I, open-label, dose-escalating trial to assess the safety and tolerability of ES2B-C001 combined with Montanide or without Montanide, in patients with human epidermal growth factor receptor 2 (HER2) expressing metastatic breast cancer.

18 years of age All Phase 1
S Sara Madrigal

A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases (CALiPSO-1)

CALiPSO-1 is a Phase 1, multi-centre, dose-confirmation study to evaluate the safety and efficacy of CNTY-101 in participants with refractory B cell-mediated autoimmune diseases including those with moderate to severe systemic lupus erythematosus (SLE)/ lupus nephritis (LN), idiopathic inflammatory myopathies (IIM), and diffuse cutaneous systemic sclerosis (DcSSc).

17 years of age All Phase 1

The Effect of Stress Ball Intervention During Non-Stress Test on Anxiety and Fetal Well-Being in High-Risk Pregnancy

This research will be conducted to determine the effect of stress ball intervention during NST on anxiety and fetal well-being in high-risk pregnant women. Women with high-risk pregnancies randomly assigned to intervention (n=43) and control (n=43) groups at a state and a faculty hospital in Turkey will be included in …

18 - 45 years of age Female Phase N/A

Study Designed to Assess the Safety and Feasibility of the Levita Magnetic Surgical System in Laparoscopic Gynecological Procedures

A study at multiple centers to evaluate the safety and practicality of the Levita Magnetic Surgical System for use in laparoscopic gynecological surgeries.

18 years of age Female Phase N/A
C Catherine Borror, BS, CCRP

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder.

18 years of age All Phase N/A
N Nicolas Belhomme, Dr

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis

Sarcoidosis is a systemic granulomatous disease of unknown aetiology, mainly affecting the lungs and lymphatics. It affects people worldwide (incidence, 4.7-64/100000; prevalence, 1-36/100000/year). Although it is most often a benign acute or subacute condition, sarcoidosis may progress to a disabling chronic disease in 25% of the cases, with severe complications …

18 years of age All Phase 4
Q Qiang Xie, MD

Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET/CT in PCa Diagnosis, Recurrence, and Metastasis

To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [18F]AlF-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of prostate cancer, and to compare with [18F]F-DCFPyL.

18 - 90 years of age Male Phase N/A
M Mariam Bahgat, PhD

Internal Photobiomodulation For Management Of Temporomandibular Joint Internal Derangement

Aim of the study was to compare the efficacy of internal versus external photobiomodulation (PBM) in the management of patients with TMJ internal derangements (TMJ-ID).

20 - 40 years of age All Phase N/A
P Peter C Rossing, MD,PHD, PROF

The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients with Diabetic Kidney Disease.

The goal of this clinical trial is to to investigate whether the drug R3R01 has a beneficial effect on the amount of protein excreted in the urine in adult patients (above 18 years of age) with type 2 diabetes and resulting kidney disease. The main questions it aims to answer …

18 years of age All Phase 2
Q Qiubai Li, Professor

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

The purpose of the study is to explore the safety and efficacy of recombinant CD19xCD3 double antibody (A-319) in active/refractory systemic lupus erythematosus (SLE).

18 - 60 years of age All Phase 1

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